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637 Treffer

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  1. Detailansicht für Treffer 1 öffnen
    Whole-Genome Sequence of Streptococcus parauberis Strain SP-llh, Isolated from Cows with Mastitis in Western China
    Liu, Longhai ; Yang, Feng ; et al.
    2017
    academicJournal
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  2. Detailansicht für Treffer 2 öffnen
    Whole-Genome Sequence of Streptococcus parauberis Strain SP-llh, Isolated from Cows with Mastitis in Western China
    Liu, Longhai ; Yang, Feng ; et al.
    In: Genome Announcements ; volume 5, issue 2 ; ISSN 2169-8287, 2017
    academicJournal
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  3. Detailansicht für Treffer 3 öffnen
    Dan@_8_3.47_Orthophotographie et détail des marques numérales du poids LlH-G
    Poigt, Thibaud
    2022
    unknown
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  4. Detailansicht für Treffer 4 öffnen
    Dan@_8_3.114_Poids Mun-A (Munoaundi) et LlH-A (Llano de la Horca)
    Poigt, Thibaud
    2022
    unknown
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  5. Detailansicht für Treffer 5 öffnen
    LINKS BETWEEN LEARNERS MINDSET AND LANGUAGE LEARNING AUTONOMOUS LANGUAGE LEARNING HISTORY (LLH)
    Ariani, Nina ; Sahid, Abdul
    In: English and Literature Journal; Vol. 3 No. 1 (2016): June; 35-41, 2016
    academicJournal
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  6. Detailansicht für Treffer 6 öffnen
    Heightened Efficacy of Anidulafungin When Used in Combination with Manogepix or 5-Flucytosine against Candida auris In Vitro.
    John, LLH ; Thomson, DD ; et al.
    2023
    Online academicJournal
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  7. Detailansicht für Treffer 7 öffnen
    NOVEL APPROACH TO SEARCH DOCUMENTS USING LLH DISTANCE CALCULATION
    T, Yogameera ; Shanthi, Dr.D.
    In: SSRN Electronic Journal ; ISSN 1556-5068, 2021
    academicJournal
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  8. Detailansicht für Treffer 8 öffnen
    The comparative function of 'llh in 2 Sam 21 and the philistine war tales ; La función comparativa de אלּה en MT 2 Sam 21
    Cohen, Margaret E.
    In: Antiguo Oriente: Cuadernos del Centro de Estudios de Historia del Antiguo Oriente. 2011, 9, 2011
    Online academicJournal
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  9. Detailansicht für Treffer 9 öffnen
    Appendix 1—figure 2. A putative circuit diagram HEC = Hunger Encoding Circuit, SEC = Satiety Encoding Circuit, which should have anti-correlated activities and report the animal's energy/caloric status. ; The cH represents both hunger and satiety state and primes the LH during hunger. It may drive other behaviors such as exploration or aversive behavior, but also suppresses feeding. Other HEC components may also be involved in LH priming/sensitization. We propose mutual inhibition between the cH and LH, though we have only demonstrated unidirectional inhibition (cH on lLH) thus far. The mLH, normally responsive to food cues, may promote hunting, though not necessarily coupled with ingestion, whereas the lLH, which is more responsive to ingestive cues, should enhance further ingestion (i.e. eating). The LH ‘gate’ is a conceptual representation of how its sensitivity to food cues could be modulated by other signals (i.e. reduced by the SEC and enhanced by cH-mediated priming). It does not necessarily represent a physical neuronal population.
    2019
    unknown
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  11. Detailansicht für Treffer 11 öffnen
    Figure 2—figure supplement 1. Modulation of cH, mLH and lLH activity in relation to feeding. ; The dataset (n = 41 fish) includes animals food-deprived for 30 min (n = 16), 2 hr (n = 11), or 4 hr (n = 14), and subsequently fed labeled paramecia for 15 min. Brains from these animals were individually-stained with anti-pERK antibody in multi-well plates in order to correlate each fish's food intake with cH, mLH and lLH neural activity. (a) Gut fluorescence (i.e. food intake) of all fish as a function of mean cH pERK fluorescence, mean LH (mLH and lLH) anti-pERK staining average fluorescence and active cell count. Mean pERK fluorescence reflects the average fluorescence within the cH, mLH or lLH regions of interest. This dataset was not normalized. Each datapoint represents an individual fish. (b) Top: mLH and lLH mean pERK fluorescence (left), and active cell count (right) of all fish (n = 41) plotted as a function of food deprivation time (denoted by color intensity). Bottom: mLH and lLH mean fluorescence (left) and cell count (right) of all fish (n = 41) plotted as a function of gut fluorescence (i.e. food intake) after 15 min of feeding (denoted by color intensity). (c-e) Quantification of gut fluorescence, cH and LH mean pERK fluorescence and LH active cell count across the different food deprivation times (30 min, 2 hr, and 4 hr). Note that in this dataset, because anti-pERK was conducted on each brain individually, there is higher variance between specimens and reduced statistical significance in cH quantification data (compare with Figure 2b, left panel). Asterisks denote p
    2019
    unknown
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  12. Detailansicht für Treffer 12 öffnen
    Figure 1—figure supplement 2. Characterization of neuronal transmitter types in the zebrafish lateral hypothalamus. ; (a) Glutamatergic and GABAergic neuron distribution in the hypothalamus. Tg(VGlut2a:dsRed) and Tg(GAD1b:GFP) transgenic fish were dissected, imaged and registered onto a common reference hypothalamus. All fish in this figure were food-deprived for 2 hr and fixed for analysis after 15 min of feeding. (b) Glutamatergic cells, labeled by Tg(VGlut2a:dsRed), overlap with active (pERK-positive) neurons in both the lLH and outer rim of the mLH. (i) Z-projection of hypothalamus. (ii) Higher magnification images of LH (iii-iv) Inset showing overlap of lLH and outer rim of mLH with glutamatergic cells. (c) GABAergic cells, labeled by Tg(Gad1b:GFP), overlap with active neurons in the inner rim of the mLH but not the lLH. (i) Z-projection of hypothalamus. (ii) Higher magnification images of LH showing a subset of z-planes. (iii-iv) Inset showing overlap of inner rim of mLH with GABAergic cells. White arrows point to examples of overlapping cells. All fish were mounted ventral side up. Scale bar (i and ii) = 50 μm. Inset (iii and iv) scale bar = 20 μm.
    2019
    unknown
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  13. Detailansicht für Treffer 13 öffnen
    Figure 3—figure supplement 3. Calcium imaging of the cH and LH over food deprivation. ; Note that fish were imaged ~20 min after embedding, thus initial food deprivation time is already 20 min. Hence, the initial reduction in LH active cell count, which occurs within 30 min (Figure 2) may not be observable using this imaging method. (a) Fish 1 and 2 were imaged using volumetric imaging for 115 min, whereas fish 3 and 4 were imaged only at a single plane, and for a slightly shorter time period of 90 min (see images in (b)) (i): Mean Δf/f across the entire (both lobes) of the cH, mLH and lLH (i.e. raw) show increases in baseline fluorescence over time. (ii) Mean Δf/f with baseline subtracted (i.e. detrended). Since a rising baseline over long imaging periods is difficult to interpret (see text for discussion), we also display detrended traces. (b) (i): Average intensity projection images showing imaged regions with ROIs outlined. (ii) Spike-triggered averages based on extracted lLH calcium spikes (from detrended traces) usually reveal an accompanying reduction in cH calcium fluorescence (Δf/f). (c) Calcium spike frequency (spikes/min, left) and calcium spike amplitude (Δf/f %, right) for each ROI averaged over 5 min bins throughout the imaging session for the above four fish. Colored lines are the means, shaded areas reflects SEM. (d) Over the entire imaging period, calcium spike frequency (left) was significantly higher in the cH as compared to the mLH (p = 0.014) and lLH (p = 0.014). Calcium spike amplitude (right) was also significantly higher in the cH as compared to the mLH (p = 0.014), but not the lLH (p = 0.057), asterisks denote p
    2019
    unknown
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  14. Detailansicht für Treffer 14 öffnen
    Figure 5. Optogenetic cH stimulation reduces lLH activity in tethered fish. ; (a) ReaChR activation of neurons. Top Panels: Targeted 633 nm laser illumination (see Materials and methods) of a defined cH area (imaged area) in Tg(y333:Gal4;UAS:ReaChR-RFP; UAS:GCaMP6s) fish. These animals express a Tg(UAS:GCaMP6s) reporter in the cH under Tg(y333:Gal4) control. The animals were subjected to repetitive 10 s laser illumination, with a periodicity of 120 s. Following the 633 nm laser pulses, there is widespread induction of cH activity, as indicated by GCaMP fluorescence (Δf/f) in most regions of interest plotted to the right of the image panel. Scale bar = 50 μm. Bottom Panel: Mean Δf/f across the entire outlined cH region versus time. Laser illumination pulses are indicated by orange bars. Gray bars indicate pre- and post-stimulation periods for which metrics shown in (c–e) were determined. (b) Inhibition of LH activity by activation of cH neurons in Tg(y333:Gal4;UAS:ReaChR-RFP; HuC:GCaMP6s) fish. The animals were subjected to repetitive 10 s laser illumination, with a periodicity of 180 s. Laser pulses were delivered to the cH (orange lightning symbol) as in a, and calcium imaging was recorded from the indicated LH areas (white outlines). Region of interest traces are shown to the right of the image panel for the indicated areas (cells and neuropil (NP)). There is an apparent reduction of spontaneous lLH GCaMP fluorescence spikes in the post-stimulation period. Scale bar = 50 μm. Bottom: Mean Δf/f across mLH and lLH ROIs over time. (c–e) Comparison of mean, summed and maximum Δf/f metrics for a 90 s window before and after ReaChR stimulation (gray bars in bottom panels in a and b). Each data point represents a single stimulation event, like those shown in a and b. Asterisks denote p
    2019
    unknown
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  15. Detailansicht für Treffer 15 öffnen
    Figure 3. Caudal and lateral hypothalamic responses to prey sensory cues are anti-correlated over short timescales. ; (a) Top: Transgenic fish (2 hr food-deprived) with GCaMP6s expressed in cH and LH neurons were paralyzed, tethered in agarose with their eyes and nostrils freed and exposed to live paramecia (prey), as described in Materials and methods. Top image: GCaMP expression in the cH and LH driven by two transgenic lines, Tg(116A:Gal4) and Tg(76A:Gal4) respectively. Bottom image: Downsampled image stack used for analysis in (f). (b) Top: Mean calcium activity (Δf/f) from respective hypothalamic ROIs (shown in (a)) from four individual fish during a baseline food-deprived period (Dep.), exposure to water alone (Water), and a dense water drop of paramecia (Para). Traces from left and right hypothalamic lobes of the same animal are overlain, revealing a high degree of correlated activity on opposite sides of the midline. Paramecia presentation increases activity in the LH and reduces activity in the cH, revealing opposing activity on short timescales. Bottom: Δf/f traces within area marked by gray box (top), displayed at higher magnification. An increase in LH activity and corresponding reduction in cH activity is observable within seconds of paramecia presentation, except for fish D in which maximal responses only occur after a few minutes (beyond the displayed time window). (c) Average Δf/f triggered on lLH calcium spikes (left and right lobes averaged) shows a mean corresponding reduction in cH activity (n = 159 lLH spikes extracted from mean Δf/f traces from 14 fish across the entire duration of the experiment). (d) Raster plots showing mean calcium activity from the hypothalamic lobes (left and right lobes averaged) of 14 fish before and after presentation of water alone and water with paramecia. (e) Quantification of integrated fluorescence (sum Δf/f %), calcium spike frequency (spikes/min) and calcium spike amplitude (Δf/f %) per fish across experimental epochs (300 s food-deprived baseline (D), 300 s after water (W) delivery or 600 s after paramecia delivery (P)). Each colored line represents data from an individual fish (left and right lobes averaged). Water alone was sufficient to significantly reduce cH integrated fluorescence (p = 6.1×10−5) and spike frequency (p = 0.0127) but not spike amplitude (p = 0.9324). Water alone was similarly sufficient to increase lLH integrated fluorescence (p = 0.029) and spike frequency (p = 0.0098) but not spike amplitude (p = 0.13). Conversely, water alone was not sufficient to significantly modulate mLH integrated fluorescence (p = 0.48) or spike frequency (p = 0.20), but was sufficient to increase spike amplitude (p = 0.039). Paramecia delivery significantly increased mLH and lLH integrated fluorescence (mLH, p = 1.2×10−4; lLH, p = 0.045) and spike frequency (mLH, p = 6.1×10−5; lLH, 6.1 × 10−4), while only significantly increasing mLH spike amplitude (mLH, p = 0.045; lLH, p = 0.43), relative to water delivery. In contrast, paramecia delivery significantly reduced cH integrated fluorescence relative to water delivery alone (p = 3.1×10−4), but not spike frequency (p = 0.52) nor spike amplitude (p = 0.85). Asterisks denote p
    2019
    unknown
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  16. Detailansicht für Treffer 16 öffnen
    Figure 3—figure supplement 2. Overlap of 116A:Gal4 and 76A:Gal4 driven reporter expression with hypothalamic activity under conditions of food deprivation and feeding. ; (a) mLH and lLH activity in voraciously-feeding (food-deprived 2 hr + 15 min paramecia) fish overlaps with Tg(76A:Gal4;UAS:GCaMP6s) expression (green, dissected brains). All visible pERK-positive neurons (magenta) were also co-labeled with GCaMP6s. Tg(116A:Gal4) is also expressed (green). Scale bar = 50 μm. (b) mLH and lLH activity in voraciously-feeding fish overlaps with Tg(76A:Gal4;UAS:GCaMP6s) expression (whole-mount). All visible pERK-positive neurons were also co-labeled with GFP. Note that more dorsally and anteriorly (as visible in the third panel of (i), and the z-projection in (ii)) other neurons beyond the LH are labeled by Tg(76A:Gal4;UAS:GCaMP6s). Scale bar = 50 μm. (c) pERK-positive cells (magenta) in 2 hr food-deprived fish overlap partially with Tg(116A:Gal4) expression (green, dissected brains). (i) Overlap with Tg(116A:Gal4;UAS:GFP) (ii) Overlap with Tg(116A:Gal4;UAS:nfsb-mCherry). Scale bar = 20 μm.
    2019
    unknown
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  17. Detailansicht für Treffer 17 öffnen
    Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents
    Duque, JSR ; Wang, X ; et al.
    2022
    Online academicJournal
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  18. Detailansicht für Treffer 18 öffnen
    Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents (vol 13, 3700, 2022)
    Rosa Duque, JS ; Wang, X ; et al.
    2022
    Online academicJournal
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  19. Detailansicht für Treffer 19 öffnen
    Maternal Cigarette Smoking During Pregnancy and Genital Anomalies in Boys: A Register-Based Cohort and Sibling-Matched Design Study
    Lindbo, D ; Arendt, LH ; et al.
    In: Clinical Epidemiology, Vol Volume 14, Pp 901-910 (2022, 2022
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  20. Detailansicht für Treffer 20 öffnen
    The Efficacy of Transdermal Rivastigmine in Mild to Moderate Alzheimer’s Disease with Concomitant Small Vessel Cerebrovascular Disease: Findings from an Open-Label Study
    Yatawara, C ; Zailan, FZ ; et al.
    In: Clinical Interventions in Aging, Vol Volume 16, Pp 301-309 (2021, 2021
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