Indirect- and direct-acting mutagenicity of diesel, coal and wood burning-derived particulates and contribution of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons
In: Mutation Research - Genetic Toxicology & Environmental Mutagenesis, Jg. 695 (2010), Heft 1/2, S. 29-34
academicJournal
Zugriff:
Abstract: Particulates exhausted from two types of diesel engines (DEPs), burning-derived particulates from three types of coal (CBPs) and burning-derived particulates from three types of wood (WBPs) were separated into four fractions by silica-gel column chromatography using n-hexane, n-hexane–dichloromethane (3:1, v/v), dichloromethane and methanol, as the corresponding eluents. The indirect-acting mutagenicity of each fraction was assayed by the Ames test using the Salmonella typhimurium TA100 strain with S9 mix and the direct-acting mutagenicity was assayed using the S. typhimurium TA98 strain without S9 mix. The polycyclic aromatic hydrocarbons (PAHs) and nitropolycyclic aromatic hydrocarbons (NPAHs) of each fraction were determined by high-performance liquid chromatography (HPLC). Both direct- and indirect-acting of mutagenicities were the highest in samples of DEPs. The contributions of PAHs in samples of WBPs and NPAHs in DEPs were the largest, respectively. [Copyright &y& Elsevier]
| Titel: |
Indirect- and direct-acting mutagenicity of diesel, coal and wood burning-derived particulates and contribution of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons
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| Autor/in / Beteiligte Person: | Yang, Xiao-Yang ; Igarashi, Kazuhiko ; Tang, Ning ; Lin, Jin-Ming ; Wang, Wei ; Kameda, Takayuki ; Toriba, Akira ; Hayakawa, Kazuichi |
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| Zeitschrift: | Mutation Research - Genetic Toxicology & Environmental Mutagenesis, Jg. 695 (2010), Heft 1/2, S. 29-34 |
| Veröffentlichung: | 2010 |
| Medientyp: | academicJournal |
| ISSN: | 1383-5718 (print) |
| DOI: | 10.1016/j.mrgentox.2009.10.010 |
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