Minimizing Erythropoietin Stimulating Agents (ESA) Requirement by Comprehensive Clinical Care.
In: Blood Purification, Jg. 41 (2016), Heft 1-3, S. 235-235
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academicJournal
Zugriff:
Topic: Chronic Kidney Disease. Background: Anemia is a common problem in children with chronic kidney disease (CKD). The objective of this study was to evaluate prevalence of anemia, use of iron supplement and erythropoietin stimulating agents (ESA) in children with CKD stage 2-5, and compare the same with previous pediatric studies. Methods: This is a retrospective chart review of children with CKD stage 2-5 (defined per KDOQI), aged between 1-18 years followed at Children's Hospital of Michigan (CHM) from January 2013 to January 2014. Data on iron saturation, hemoglobin level, use of iron supplements and ESA was collected. Results: Total number of patients was 60. The mean age was 10.3 years (±5.54) and 30% were female. The main causes of CKD were cystic/dysplastic kidneys (33.3%), obstructive uropathy (20%), reflux nephropathy (15%), glomerular pathology (11.6%) and others (20%). In our cohort, 25% patients had anemia. Also, only 6.67% of CKD patients were on ESA, compared to 18% in Ckid study and 19.5% in study by Wong et al. Conclusion: Our CKD patients had a lower prevalence of anemia and lower use of ESA compared to other pediatric studies. We maintain adequate iron stores by using iron supplements even in children with normal hemoglobins. The administration of supplemental iron prior to the development of anemia in children with CKD decreases the need for ESA. [ABSTRACT FROM AUTHOR]
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Minimizing Erythropoietin Stimulating Agents (ESA) Requirement by Comprehensive Clinical Care.
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Autor/in / Beteiligte Person: | Dhull, R. ; Baracco, R. ; Gregory, M. J. ; Mattoo, T. K. |
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Zeitschrift: | Blood Purification, Jg. 41 (2016), Heft 1-3, S. 235-235 |
Veröffentlichung: | 2016 |
Medientyp: | academicJournal |
ISSN: | 0253-5068 (print) |
DOI: | 10.1159/000442341 |
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