Unique cascade ring-opening/cyclization reaction of azlactones and DBU or DBN: Synthesis of new pyrrolam A analogues.
In: Tetrahedron, Jg. 73 (2017-03-16), Heft 11, S. 1397-1406
academicJournal
Zugriff:
1-Azabicyclo[3.3.0]oct-3-en-2-one derivatives were synthesized efficiently through the facile cascade reaction of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) or 1,5-diazabicyclo[4.3.0]non-5-ene (DBN) with arylidene azlactones. This research provides a straightforward procedure for the synthesis of a novel class of multicyclic semi-alkaloids which shows good antimicrobial activity. Under catalyst-free, mild, and solventless condition, a wide range of fused tricyclic derivatives was obtained in high yields. [ABSTRACT FROM AUTHOR]
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Unique cascade ring-opening/cyclization reaction of azlactones and DBU or DBN: Synthesis of new pyrrolam A analogues.
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Autor/in / Beteiligte Person: | Parhizkar, Golnaz ; Khosropour, Ahmad Reza ; Mohammadpoor-Baltork, Iraj ; Parhizkar, Elahehnaz ; Rudbari, Hadi Amiri |
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Zeitschrift: | Tetrahedron, Jg. 73 (2017-03-16), Heft 11, S. 1397-1406 |
Veröffentlichung: | 2017 |
Medientyp: | academicJournal |
ISSN: | 0040-4020 (print) |
DOI: | 10.1016/j.tet.2017.01.036 |
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