Abstract 17227: Atrial Fibrillation in the Presence of Post-ST Segment Elevation Myocardial Infarction Left Ventricular Thrombus is Associated With Worse Outcomes.
In: Circulation, Jg. 138 (2018-11-07), S. A17227
Online
academicJournal
Zugriff:
Introduction: Left ventricular (LV) thrombus is a complication of ST-segment elevation myocardial infarction (STEMI) that leads to a higher risk of stroke. Atrial fibrillation (AF) is another independent risk factor for stroke, however there is a dearth of studies examining the outcomes of patients with concomitant AF and LV thrombus. Hypothesis: This study aims to investigate the impact of the presence of concomitant AF in post-STEMI patients with an LV thrombus on stroke and mortality outcomes. Methods: We screened 6007 transthoracic echocardiogram reports containing the "thrombus" keyword from July 2006 to September 2017. Relevant clinical data was collected from 196 post-STEMI patients positive for an LV thrombus, stratified into non-AF and AF groups. Results: AF patients (69.6 ± 11.8 years) were significantly older (p < 0.01) than non-AF patients (55.5 ± 12.2 years) and more were found to have chronic kidney disease (p = 0.02), hypertension (p = 0.04) and dyslipidaemia (p = 0.03), with significantly higher baseline HAS-BLED score (p < 0.01) and CHA2DS2-VASc score (p < 0.01). Fewer AF patients were treated with triple therapy (p = 0.04). Despite this, there was no difference observed in resolution of the LV thrombus on repeat imaging (p = 0.30). However, Kaplan-Meier analysis showed a higher incidence of stroke (p = 0.02) and all-cause mortality (p < 0.01) in AF patients. Conclusion: Post-STEMI patients with LV thrombus formation and AF have significant differences from non-AF patients and are associated with poorer outcomes. These findings should be validated in larger cohorts. [ABSTRACT FROM AUTHOR]
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Abstract 17227: Atrial Fibrillation in the Presence of Post-ST Segment Elevation Myocardial Infarction Left Ventricular Thrombus is Associated With Worse Outcomes.
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Autor/in / Beteiligte Person: | Leow, Aloysius Shen-Ting ; Sia, Ching-Hui ; Yeo, Leonard Leong-Litt ; Tan, Benjamin Yong-Qiang ; Kaur, Rajinderdeep ; Sim, Hui-Wen ; Yeo, Tiong-Cheng ; Chan, Mark Yan-Yee ; Tay, Edgar Lik-Wui ; Loh, Joshua Ping-Yun |
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Zeitschrift: | Circulation, Jg. 138 (2018-11-07), S. A17227 |
Veröffentlichung: | 2018 |
Medientyp: | academicJournal |
ISSN: | 0009-7322 (print) |
DOI: | 10.1161/circ.138.suppl_1.17227 |
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