Synthetic ubiquitinated proteins meet the proteasome: Distinct roles of ubiquitin in a chain.
In: Proceedings of the National Academy of Sciences of the United States of America, Jg. 116 (2019-04-16), Heft 16, S. 7614-7616
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Zugriff:
The article offers information on the roles of ubiquitin (Ub) in the proteasome system. Topics discussed include information on the proteasome consists of a cylindrical 20S core particle responsible for catalytic protein degradation; discussions on the use of the epoxomicin introduced bto inhibit proteasome; and the information on the emergence of technologies to prepare Ub-based reagents, poly-Ub chains, and ubiquitinated proteins.
Titel: |
Synthetic ubiquitinated proteins meet the proteasome: Distinct roles of ubiquitin in a chain.
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Autor/in / Beteiligte Person: | van der Heden van Noort, Gerbrand J. ; Gan, Jin ; Ovaa, Huib |
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Zeitschrift: | Proceedings of the National Academy of Sciences of the United States of America, Jg. 116 (2019-04-16), Heft 16, S. 7614-7616 |
Veröffentlichung: | 2019 |
Medientyp: | academicJournal |
ISSN: | 0027-8424 (print) |
DOI: | 10.1073/pnas.1903405116 |
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