BTV antibody longevity in cattle five to eight years post BTV-8 vaccination.
In: Vaccine, Jg. 37 (2019-05-06), Heft 20, S. 2656-2660
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Zugriff:
The Bluetongue virus serotype −8 (BTV-8) epizootic in Germany (2006–2008) was successfully eradicated, essentially by the massive application of commercially available inactivated BTV-8 vaccines. While a six-year antibody longevity of BTV antibodies post BTV-8 vaccination in cattle has been described previously, our study investigated the BTV-8-vaccine antibodies in cattle for up to eight years. In total, 157 bovine serum samples were analysed for the presence of group-specific BTV antibodies in both a commercial cELISA, and a BTV-8- specific serum neutralization test. A robust number of cattle were seropositive for group- and serotype-specific neutralising antibodies for five or more years. In selected animals, born and vaccinated in 2009 or later, the presence of BTV antibodies for up to eight years post BTV-8 vaccination could be confirmed. Our data also show, that booster vaccination prolonged the antibody longevity of vaccine-induced antibodies and the number of serologically positive cattle. [ABSTRACT FROM AUTHOR]
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BTV antibody longevity in cattle five to eight years post BTV-8 vaccination.
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Autor/in / Beteiligte Person: | Ries, Christina ; Beer, Martin ; Hoffmann, Bernd |
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Zeitschrift: | Vaccine, Jg. 37 (2019-05-06), Heft 20, S. 2656-2660 |
Veröffentlichung: | 2019 |
Medientyp: | academicJournal |
ISSN: | 0264-410X (print) |
DOI: | 10.1016/j.vaccine.2019.03.082 |
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