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Triglyceride-glucose index on risk of adverse events after drug-coated balloon angioplasty.
In: Lipids in Health & Disease, Jg. 22 (2023-10-28), Heft 1, S. 1-11
Online
academicJournal
Zugriff:
Background: The pathogenetic mechanism of atherosclerotic cardiovascular diseases is associated with insulin resistance (IR), which serves as a metabolic risk factor. As a novel indication for IR, triglyceride-glucose (TyG) index may predict cardiovascular disease outcomes. Methods: In current study, a cohort of 157 individuals with newly developed de novo lesions who received DCB angioplasty between January 2017 and May 2021 were included. The midterm follow-up clinical results consisted of the presence of vessel-oriented composite endpoint (VOCE). The baseline TyG index was divided into three groups by tertiles. This study compared various clinical characteristics and parameters among different groups during DCB angioplasty. A multivariate Cox regression model was built to investigate the potential predictors. Results: Higher TyG index indicated an increased risk of VOCE according to the adjusted model (HR = 4.0, 95%Cl: 1.0-15.4, P = 0.047). A non-linear correlation was uncovered between the index and VOCE from the smooth curve. Based on Kaplan-Meier curve, individuals in the highest TyG index group were more likely to develop VOCE (P < 0.05 for log-rank). Conclusions: The incidence of VOCE was shown to be independently and positively correlated with an elevated TyG index in individuals with de novo coronary lesions who received DCB angioplasty. [ABSTRACT FROM AUTHOR]
Titel: |
Triglyceride-glucose index on risk of adverse events after drug-coated balloon angioplasty.
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Autor/in / Beteiligte Person: | Lin, Zhaorong ; He, Xi ; Lin, Maosen ; Chen, Lianglong |
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Zeitschrift: | Lipids in Health & Disease, Jg. 22 (2023-10-28), Heft 1, S. 1-11 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1476-511X (print) |
DOI: | 10.1186/s12944-023-01951-8 |
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