1990--2019年全球归因于低体力活动心血管疾病负担 及变化趋势.

Objective To assess the burden of cardiovascular disease (CVD) caused by low physical activity and related trends at the global, regional, and national levels, to provide guidance for global prevention priority actions. Methods Based on the Global Burden of Disease (GBD) study in 2019, data on CVD burden attributable to low physical activity were extracted and investigated. Age standardized rate (ASR) was used to make comparison between mortality and disability adjusted life years (DALYs) in different populations, and age standardized death rate (ASDR) and the age-standardized rate (ASR) of standardized DALY rates were quantitatively evaluated by estimated annual percentage change (EAPC). Results From 1990 to 2019, the ASDR (EAPC=-1.44, 95%CZ: -1.50 to 137) and DALY standardized rate (EAPC=-130, 95%CI: -135 to -1.25) of CVD decreased due to low physical activity, and the standardized rate of DALY in males was higher than that in females. There was a consistent downward trend in the five socio demographic index (SDI) areas, and with the improvement of SDI, the decline gradually increased, with the highest decline in the areas with high SDI (EAPC二一3.47, EAPC=-3.06). Of the 21 geographical regions and 204 countries, the highest standardized rates of ASDR and DALY per 100 000 people of CVD attributed to low physical activity in 2019 were in North Africa and the Middle East, and the highest was in Sudan. Sub-Saharan Africa (EAPC =0.18, EAPC =0.44) experienced the largest increase from 1990 to 2019, with the largest increase in Uzbekistan (EAPC=3.37, EAPC=3.11) and. the largest decline in South Korea (EAPC=-4>60!) EAPC=-4.89). Conclusion Although the global disease burden of CVD attributed to low physical activity decreased from 1990 to 2019, which was higher in males than in females, mainly between 70 and 94 years old, it is higher in some high -and middle -income countries, mainly in North Africa and the Middle East, Central and Eastern Europe and Sudan, Oman, Saudi Arabia, and Qatar. Although the disease burden of CVD attributed to low physical activity in China has decreased, the standardized mortality rate is still on the rise. There is an urgent need for strong public health interventions to prevent low physical activity, reduce sedentary time, and carry out science education, especially for elderly people with lower amount of exercise than recommended, males, and the obese due to occupational low physical activity. [ABSTRACT FROM AUTHOR]

目的 本研究从全球、地区和国家层面评估由低体力活动引起的心血管疾病(cardiovascular disease,CVD)负担以 及相关变化趋势, 为全球预防优先行动提供指导。方法 基于2019年全球疾病负担研究(GBD)提取并研究了可归因于 低体力活动的CVD负担的数据, 采用年龄标准化率(age standardized rate, ASR)£F同人群实现死亡率和残疾调整生命 年(disability-adjusted life years,DALYs)之间进行合理的比较, 通过估计的年度百分比变化(estimated annual percentage change,EAPC)量化评估年龄标化死亡率(age-standardized death rate, ASDR)和标化DALY率的年龄标准化率(ASR)趋 势。结果1990--2019年因低体力活动导致CVD的ASDR (EAPC = -1.44;95%C7：-1.50 ~ -1.37)和DALY标化率 (EAPC = -1.30;95%：-1.35 ~ -1.25)呈下降趋势, 且男性高于女性。在5个社会人口指数(SDI)地区呈现岀一致的下 降趋势, 随着SDI的改善, 下降幅度逐渐增大, 高SDI地区下降幅度最多(EAPC=-3.47;EAPC=-3.06)o在21个地理区域 和204个国家中,2019年归因于低体力活动的CVD每10万人ASDR和DALY标化率最高的地区均是北非和中东, 最 高的国家均为苏丹。1990--2019年增幅最多地区撒哈拉以南非'|(EAPC=0.18;EAPC=0.44),增幅最大的国家为乌兹别 克斯坦(EAPC=3.37;EAPC =3.11);降幅最大国家为韩g(EAPC=-4.60; EAPC=-4.89)O 结论 尽管 1990--2019 年可归 因于低体力活动的CVD全球疾病负担有所下降,男性高于女性, 集中发生在70~94岁之间, 但在一些中高冲等收人 国家地区较高, 主要是北非和中东、中亚东欧和苏丹、阿曼、沙特阿拉伯、卡塔尔, 虽然中国归因于低体力活动的CVD的 疾病负担有所下降, 但标化死亡率仍呈现上升趋势, 也迫切需要采取强有力的公共卫生干预举措, 预防低体力活动, 减 少久坐时间,进行科学教育, 特别是运动量低于推荐老年人群或因职业低体力活动的男性、肥胖者. [ABSTRACT FROM AUTHOR]