High-Performance Liquid Chromatographic Determination of Proquazone and Its m-Hydroxy Metabolite in Spiked Human Plasma and Urine.
In: Journal of AOAC International, Jg. 90 (2007-07-01), Heft 4, S. 971-976
Online
academicJournal
Zugriff:
The article describes a high-performance liquid chromatography method for the analysis of proquazone (PQZ) and its major metabolite, m-hydroxyproquazone, in spiked human plasma and urine by direct injection into an RP C8 column without any extraction procedure. According to the authors, only a single preparation step of protein precipitation for the plasma samples is performed before injection into the column. They add the proposed method was used for the assay of PQZ in laboratory-made tablets.
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High-Performance Liquid Chromatographic Determination of Proquazone and Its m-Hydroxy Metabolite in Spiked Human Plasma and Urine.
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Autor/in / Beteiligte Person: | Hassan, Ekram M. ; Gazy, Azza A. ; Abdel-Hay, Mohamed H. ; Belal, Tarek S. |
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Zeitschrift: | Journal of AOAC International, Jg. 90 (2007-07-01), Heft 4, S. 971-976 |
Veröffentlichung: | 2007 |
Medientyp: | academicJournal |
ISSN: | 1060-3271 (print) |
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