Unveiling a Complex Phase Transition in Monolayers of a Phospholipid from the Annular Region of Transmembrane Proteins.
In: Journal of Physical Chemistry B, Jg. 111 (2007-09-20), Heft 37, S. 10946-10951
academicJournal
Zugriff:
The lateral packing properties of phospholipids that surround transmembrane proteins are fundamental in the biological activity of these proteins. In this work, Langmuir monolayers of one such lipid, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE), are studied with a combination of pressure−area isotherm analysis, Brewster angle microscopy, and atomic force microscopy of extracted films. The analysis reveals a sequence of phase transitions LE−LC−LC‘ occurring in a narrow packing range. The lateral pressures and area densities of these phases provided meanings for the packing requirements in the annular lipid region of typical transmembrane proteins. [ABSTRACT FROM AUTHOR]
Titel: |
Unveiling a Complex Phase Transition in Monolayers of a Phospholipid from the Annular Region of Transmembrane Proteins.
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Autor/in / Beteiligte Person: | Domènech, Òscar ; Ignés-Mullol, Jordi ; M. Teresa Montero ; Hernandez-Borrell, Jordi |
Zeitschrift: | Journal of Physical Chemistry B, Jg. 111 (2007-09-20), Heft 37, S. 10946-10951 |
Veröffentlichung: | 2007 |
Medientyp: | academicJournal |
ISSN: | 1520-6106 (print) |
DOI: | 10.1021/jp0721144 |
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