Proline catalyzed direct diastereoselective 6-enolexo aldolization: toward the synthesis of the imino sugar DNJ
In: Tetrahedron: Asymmetry, Jg. 21 (2010-11-25), Heft 21/22, S. 2703-2708
academicJournal
Zugriff:
Abstract: A l-proline catalyzed direct diastereoselective 6-enolexo aldolization reaction of differentiating dialdehydes derived from tartaric acid is presented. This organocatalytic approach provides high levels of syn-selectivity (dr >10:1) with the stereocontrolled C–C bond formation between C4 and C5 intramolecularly, which can serve to synthesize imino-sugar skeleton quickly. [ABSTRACT FROM AUTHOR]
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Proline catalyzed direct diastereoselective 6-enolexo aldolization: toward the synthesis of the imino sugar DNJ
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Autor/in / Beteiligte Person: | Kumar, Indresh ; Rode, Chandrashekhar V. |
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Zeitschrift: | Tetrahedron: Asymmetry, Jg. 21 (2010-11-25), Heft 21/22, S. 2703-2708 |
Veröffentlichung: | 2010 |
Medientyp: | academicJournal |
ISSN: | 0957-4166 (print) |
DOI: | 10.1016/j.tetasy.2010.10.024 |
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