Lymph node vascular-stromal growth and function as a potential target for controlling immunity
In: Clinical Immunology, Jg. 144 (2012-08-01), Heft 2, S. 109-116
academicJournal
Zugriff:
Abstract: Lymphadenopathy occurs in many autoimmune and inflammatory diseases, and vascular proliferation is a common feature in the enlarged lymph nodes. The lymph node vasculature plays critical roles in delivering immune cells as well as oxygen and micronutrients, and therefore represents a potential target for therapeutic manipulation of immunity. In this review, we discuss recent insights made in understanding the growth and function of the vascular and associated stromal compartment in immune-stimulated lymph nodes and the potential utility of altering this process in autoimmune diseases. [Copyright &y& Elsevier]
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Lymph node vascular-stromal growth and function as a potential target for controlling immunity
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Autor/in / Beteiligte Person: | Benahmed, Fairouz ; Ely, Scott ; Lu, Theresa T. |
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Zeitschrift: | Clinical Immunology, Jg. 144 (2012-08-01), Heft 2, S. 109-116 |
Veröffentlichung: | 2012 |
Medientyp: | academicJournal |
ISSN: | 1521-6616 (print) |
DOI: | 10.1016/j.clim.2012.05.004 |
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