Anti-cancer drug KP1019 modulates epigenetics and induces DNA damage response in Saccharomyces cerevisiae.
In: FEBS Letters, Jg. 588 (2014-03-18), Heft 6, S. 1044-1052
Online
academicJournal
Zugriff:
Highlights: [•] Histones and their modifying enzymes provide tolerance to KP019. [•] KP1019 treatment causes activation of DNA damage checkpoint kinase pathway. [•] KP1019 activates DNA damage response by inducing RNR genes. [Copyright &y& Elsevier]
Titel: |
Anti-cancer drug KP1019 modulates epigenetics and induces DNA damage response in Saccharomyces cerevisiae.
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Autor/in / Beteiligte Person: | Singh, Vikash ; Azad, Gajendra Kumar ; Mandal, Papita ; Amarendar Reddy, M. ; Tomar, Raghuvir S. |
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Zeitschrift: | FEBS Letters, Jg. 588 (2014-03-18), Heft 6, S. 1044-1052 |
Veröffentlichung: | 2014 |
Medientyp: | academicJournal |
ISSN: | 0014-5793 (print) |
DOI: | 10.1016/j.febslet.2014.02.017 |
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