Novel common variants and susceptible haplotype for exfoliation glaucoma specific to Asian population.
In: Scientific Reports, 2014-06-20, S. 1-6
Online
academicJournal
Zugriff:
The article discusses a study on the common variants in lysyl oxidase-like 1 gene (LOXL1) associated with exfoliation glaucoma (XFG) patients developed through exfoliation syndrome (XFS). It notes the risk allele of a variant in LOXL1 which has been discovered to be inverted between Asian and Caucasian population. The authors performed a genome-wide association study using 201 XFS/XFG and 697 controls and identified 34 genome-wide significant single-nucleotide polymorphisms (SNPs).
Titel: |
Novel common variants and susceptible haplotype for exfoliation glaucoma specific to Asian population.
|
---|---|
Autor/in / Beteiligte Person: | Nakano, Masakazu ; Ikeda, Yoko ; Tokuda, Yuichi ; Fuwa, Masahiro ; Ueno, Morio ; Imai, Kojiro ; Sato, Ryuichi ; Omi, Natsue ; Adachi, Hiroko ; Kageyama, Masaaki ; Mori, Kazuhiko ; Kinoshita, Shigeru ; Tashiro, Kei |
Link: | |
Zeitschrift: | Scientific Reports, 2014-06-20, S. 1-6 |
Veröffentlichung: | 2014 |
Medientyp: | academicJournal |
ISSN: | 2045-2322 (print) |
DOI: | 10.1038/srep05340 |
Schlagwort: |
|
Sonstiges: |
|