An improved method for carotid artery infusion without vessel occlusion.
In: Physiology & behavior, Jg. 52 (1992-12-01), Heft 6, S. 1211-3
academicJournal
Zugriff:
This is an simple, non-time-consuming and advantageous procedure for catheterization and drug administration in thin arteries of small animals. The cannulation method consists of implanting polyimide-coated silica capillary tubing. To avoid vascular tear during puncture, the tubing tip is beveled. The cannula is stuck to the wall of the artery without artery ligation, using a small drop of a fast cyanoacrylate adhesive. The surgical procedure can be completed in 15 min and has the following properties: 1) it is wise but not indispensable to perfuse a solution continually through the cannula; 2) the dead volume is low and drugs may be injected in a very low solution volume; 3) it is not necessary to close the lumen of the vessel during catheterization; 4) the drug solution may be perfused into a normal bloodstream and thus its kinetic behavior is not modified by undesired cul-de-sac effects presented after artery ligation.
Titel: |
An improved method for carotid artery infusion without vessel occlusion.
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Autor/in / Beteiligte Person: | Rodriguez, M ; Barroso, N |
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Zeitschrift: | Physiology & behavior, Jg. 52 (1992-12-01), Heft 6, S. 1211-3 |
Veröffentlichung: | New York NY : Elsevier Science ; <i>Original Publication</i>: Oxford, Eng., Long Island City, Pergamon Press., 1992 |
Medientyp: | academicJournal |
ISSN: | 0031-9384 (print) |
DOI: | 10.1016/0031-9384(92)90485-k |
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