Characterization of a long terminal repeat region from an infectious Indian HIV type 2 isolate.
In: AIDS research and human retroviruses, Jg. 21 (2005-06-01), Heft 6, S. 592-6
academicJournal
Zugriff:
An infectious Indian human immunodeficiency virus type 2 isolate from Mumbai, propagated in this laboratory, was found to bear an unusually short long terminal repeat (LTR) region. Complete sequencing of the 601 bp LTR indicated a loss of around 250 nucleotide pairs from the unique 3' (U3) region as compared to other well-characterized HIV-2 isolates. Phylogenetic analysis of this LTR shows closest relatedness to the Guinea-Bissau subtype A isolates HIV-2(CAM2) and HIV-2(ALI). The LTR from the biologically active infectious clone with the observed deletion contained all functionally relevant promoter and polyadenylation sequences.
Titel: |
Characterization of a long terminal repeat region from an infectious Indian HIV type 2 isolate.
|
---|---|
Autor/in / Beteiligte Person: | Tamhane, M ; Mukhopadhyaya, R |
Zeitschrift: | AIDS research and human retroviruses, Jg. 21 (2005-06-01), Heft 6, S. 592-6 |
Veröffentlichung: | Larchmont, NY : Mary Ann Liebert ; <i>Original Publication</i>: [New York] : Mary Ann Liebert, [c1987-, 2005 |
Medientyp: | academicJournal |
ISSN: | 0889-2229 (print) |
DOI: | 10.1089/aid.2005.21.592 |
Schlagwort: |
|
Sonstiges: |
|