EUS-guided fine needle aspiration with and without trucut biopsy of pancreatic masses.

Shah, SM ; Ribeiro, A ; et al.

In: JOP : Journal of the pancreas, Jg. 9 (2008-07-10), Heft 4, S. 422-30

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Context: Endoscopic ultrasound-guided trucut biopsy (EUS TCB) has a lower yield than fine needle aspiration (FNA) in pancreatic masses but the additional use of TCB to FNA may improve the diagnostic accuracy over FNA alone.

Objective: To compare the yield of EUS FNA alone or combined with EUS TCB for diagnosis of pancreatic masses.

Design: Single center retrospective case control study conducted at academic tertiary center. Study conducted between March 2004 and April 2007.

Participants: A total of 126 consecutive patients referred for EUS guided biopsy of pancreatic mass; three patients excluded from analysis, final cohort comprised 123 patients (108 malignant and 15 benign). EUS FNA was performed in 72 patients and EUS FNA+TCB was performed in 51 patients.

Main Outcome Measures: The diagnostic performance of EUS FNA versus EUS FNA+TCB was compared.

Results: The sensitivity, specificity and frequency of cases correctly identified for malignancy of FNA alone were 87.1% (54/62), 100% (10/10) and 88.8% (64/72), while for the combination of FNA+TCB they were: 95.7% (44/46), 100% (5/5) and 96.0% (49/51), respectively (P=0.184, 1.000, and 0.193 FNA versus FNA+TCB). No major complication occurred in either group.

Conclusion: FNA+TCB can be safely performed in selected lesions but sensitivity is not statistically improved over FNA alone (95.7% versus 87.1%).

Titel:	EUS-guided fine needle aspiration with and without trucut biopsy of pancreatic masses.
Autor/in / Beteiligte Person:	Shah, SM ; Ribeiro, A ; Levi, J ; Jorda, M ; Rocha-Lima, C ; Sleeman, D ; Hamilton-Nelson, K ; Ganjei-Azar, P ; Barkin, J
Link:	Full Text Finder (Volltext)
Zeitschrift:	JOP : Journal of the pancreas, Jg. 9 (2008-07-10), Heft 4, S. 422-30
Veröffentlichung:	<2018- > : London : Prime Scholars ; <i>Original Publication</i>: [Genova] : E.S. Burioni ricerche bibliografiche, [2000-, 2008
Medientyp:	academicJournal
ISSN:	1590-8577 (electronic)
Schlagwort:	Aged Case-Control Studies Female Follow-Up Studies Humans Male Middle Aged Reproducibility of Results Retrospective Studies Sample Size Sensitivity and Specificity Survival Rate Biopsy, Fine-Needle statistics & numerical data Biopsy, Needle statistics & numerical data Endoscopy statistics & numerical data Endosonography statistics & numerical data Pancreatic Diseases diagnosis Pancreatic Neoplasms diagnosis
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Comparative Study; Journal Article Language: English [JOP] 2008 Jul 10; Vol. 9 (4), pp. 422-30. <i>Date of Electronic Publication: </i>2008 Jul 10. MeSH Terms: Biopsy, Fine-Needle / statistics & numerical data ; Biopsy, Needle / statistics & numerical data ; Endoscopy / statistics & numerical data ; Endosonography / statistics & numerical data ; Pancreatic Diseases / diagnosis ; Pancreatic Neoplasms / diagnosis ; Aged ; Case-Control Studies ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Reproducibility of Results ; Retrospective Studies ; Sample Size ; Sensitivity and Specificity ; Survival Rate Entry Date(s): Date Created: 20080724 Date Completed: 20080819 Latest Revision: 20080723 Update Code: 20231215

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