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Introduction and Hypothesis: To evaluate clinical outcomes at 3 years following total transvaginal mesh (TVM) technique to treat vaginal prolapse.

Methods: Prospective, observational study in patients with prolapse ≥ stage II. Success was defined as POP-Q-stage 0-I and absence of surgical re-intervention for prolapse. Secondary outcome measures were: quality of life (QOL), prolapse-specific inventory (PSI), impact on sexual activity and complications.

Results: Ninety women underwent TVM repair, 72 a hysterectomy. Anatomical failure rate was 20.0% at 3 years. Three patients required re-intervention for prolapse. Improvements in QOL- and PSI-scores were observed at 1 and 3 years. Vaginal mesh extrusion occurred in 14.4% patients. After 3 years, 4.7% asymptomatic extrusions remained present. Of 61 sexually active women at baseline, a significant number of patients (41%) ceased sexual activity by 3 years; de novo dyspareunia was reported by 8.8%. One vesico-vaginal fistula resolved after surgery.

Conclusion: Medium-term results demonstrate that the TVM technique provides a durable prolapse repair.

Titel:	Total transvaginal mesh (TVM) technique for treatment of pelvic organ prolapse: a 3-year prospective follow-up study.
Autor/in / Beteiligte Person:	Jacquetin, B ; Fatton, B ; Rosenthal, C ; Clavé, H ; Debodinance, P ; Hinoul, P ; Gauld, J ; Garbin, O ; Berrocal, J ; Villet, R ; Salet Lizée, D ; Cosson, M
Link:	View record at Springer (Volltext)
Zeitschrift:	International urogynecology journal, Jg. 21 (2010-12-01), Heft 12, S. 1455-62
Veröffentlichung:	London : Springer, 2010
Medientyp:	academicJournal
ISSN:	1433-3023 (electronic)
DOI:	10.1007/s00192-010-1223-0
Schlagwort:	Aged Female Follow-Up Studies Gynecologic Surgical Procedures instrumentation Humans Longitudinal Studies Middle Aged Patient Satisfaction Prospective Studies Quality of Life Sexual Behavior Treatment Outcome Gynecologic Surgical Procedures methods Pelvic Organ Prolapse surgery Surgical Mesh
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Research Support, Non-U.S. Gov't Language: English [Int Urogynecol J] 2010 Dec; Vol. 21 (12), pp. 1455-62. <i>Date of Electronic Publication: </i>2010 Aug 04. MeSH Terms: Surgical Mesh* ; Gynecologic Surgical Procedures / methods ; Pelvic Organ Prolapse / surgery ; Aged ; Female ; Follow-Up Studies ; Gynecologic Surgical Procedures / instrumentation ; Humans ; Longitudinal Studies ; Middle Aged ; Patient Satisfaction ; Prospective Studies ; Quality of Life ; Sexual Behavior ; Treatment Outcome References: Am J Obstet Gynecol. 2008 May;198(5):555.e1-5. (PMID: 18355779) ; Am J Obstet Gynecol. 2008 Dec;199(6):683.e1-7. (PMID: 18828990) ; Int Urogynecol J Pelvic Floor Dysfunct. 1999;10(6):390-3. (PMID: 10614976) ; Obstet Gynecol. 2008 Apr;111(4):891-8. (PMID: 18378748) ; Am J Obstet Gynecol. 2003 Aug;189(2):372-7; discussion 377-9. (PMID: 14520198) ; Int Urogynecol J Pelvic Floor Dysfunct. 2008 Mar;19(3):383-9. (PMID: 17912473) ; Prog Urol. 2001 Dec;11(6):1306-13. (PMID: 11859672) ; Am J Obstet Gynecol. 1996 Jul;175(1):10-7. (PMID: 8694033) ; Int Urogynecol J Pelvic Floor Dysfunct. 1996;7(2):81-5; discussion 85-6. (PMID: 8798092) ; Obstet Gynecol. 2009 Feb;113(2 Pt 1):367-73. (PMID: 19155908) ; Int Urogynecol J Pelvic Floor Dysfunct. 2006 Jun;17(4):315-20. (PMID: 16228121) ; Am J Obstet Gynecol. 2008 Dec;199(6):707.e1-6. (PMID: 18977469) ; J Gynecol Obstet Biol Reprod (Paris). 2004 Nov;33(7):577-88. (PMID: 15550876) ; Am J Obstet Gynecol. 2004 Jan;190(1):20-6. (PMID: 14749629) ; Eur Urol. 2003 Dec;44(6):724-30. (PMID: 14644127) ; Am J Obstet Gynecol. 1996 Dec;175(6):1418-21; discussion 1421-2. (PMID: 8987919) ; Obstet Gynecol. 2009 Sep;114(3):600-609. (PMID: 19701041) ; Obstet Gynecol. 1997 Apr;89(4):501-6. (PMID: 9083302) ; Obstet Gynecol. 2001 Oct;98(4):646-51. (PMID: 11576582) ; Am J Obstet Gynecol. 2001 Jun;184(7):1357-62; discussion 1362-4. (PMID: 11408853) ; Int Urogynecol J Pelvic Floor Dysfunct. 2008 Dec;19(12):1611-6. (PMID: 18716704) ; Obstet Gynecol. 2009 Jan;113(1):117-126. (PMID: 19104367) ; Neurourol Urodyn. 2004;23(4):367-73. (PMID: 15227656) ; Obstet Gynecol. 2009 Jan;113(1):127-133. (PMID: 19104368) ; Am J Obstet Gynecol. 2002 Jul;187(1):56-63. (PMID: 12114889) ; Am J Obstet Gynecol. 1996 Dec;175(6):1472-5. (PMID: 8987927) ; BJOG. 2005 Jul;112(7):971-6. (PMID: 15958002) ; Int Urogynecol J Pelvic Floor Dysfunct. 2007 Jul;18(7):743-52. (PMID: 17131170) Entry Date(s): Date Created: 20100805 Date Completed: 20110310 Latest Revision: 20211020 Update Code: 20231215

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Total transvaginal mesh (TVM) technique for treatment of pelvic organ prolapse: a 3-year prospective follow-up study.