[Study of 71 cases of visceral leishmaniasis diagnosed at the Mustapha University Hospital (Algiers) from 1998 to 2009].

Zait, H ; Ferhani, Y ; et al.

In: Medecine et maladies infectieuses, Jg. 42 (2012-03-01), Heft 3, S. 119-25

academicJournal

Objective: The authors retrospectively studied the epidemiological, clinical, diagnostic and therapeutic aspects of 71 cases of visceral leishmaniasis from 1998 to 2009.

Population and Methods: The diagnosis was made by finding Leishmania amastigotes in bone marrows smears and/or by serology.

Results: Most cases occur in winter (35.2%) and in spring (36.6%). The source areas are endemic ones located in the north of Algeria (74.6%) and more rarely arid or semi-arid climate areas (8.4%). 88.7% of patients are children. The sex ratio is 1.53. The clinical characteristics are: fever (77.4%), paleness (43.6%); splenomegaly (83%), hepatomegaly (57.7%). The biological anomalies are: anemia (56.3%), thrombocytopenia (33.8%), and leucopenia (28.1%). N-methylglucamine (Glucantime(®)) was most often prescribed (70.4%). Four deaths (5.6%) were recorded.

Conclusion: Visceral leishmaniasis remains a pediatric affection but does not spare adults.

Titel:	[Study of 71 cases of visceral leishmaniasis diagnosed at the Mustapha University Hospital (Algiers) from 1998 to 2009].
Autor/in / Beteiligte Person:	Zait, H ; Ferhani, Y ; Achir, I ; Hamrioui, B
Zeitschrift:	Medecine et maladies infectieuses, Jg. 42 (2012-03-01), Heft 3, S. 119-25
Veröffentlichung:	Paris : Elsevier ; <i>Original Publication</i>: Paris, Société française d'éditions médicales., 2012
Medientyp:	academicJournal
ISSN:	1769-6690 (electronic)
DOI:	10.1016/j.medmal.2012.01.001
Schlagwort:	Adolescent Adult Age Distribution Aged Algeria epidemiology Animals Antiprotozoal Agents therapeutic use Bone Marrow parasitology Child Child, Preschool Dog Diseases epidemiology Dog Diseases parasitology Dogs parasitology Endemic Diseases Humans Infant Insect Vectors parasitology Leishmania infantum isolation & purification Leishmaniasis, Visceral diagnosis Leishmaniasis, Visceral transmission Leishmaniasis, Visceral veterinary Middle Aged Phlebotomus parasitology Retrospective Studies Sex Distribution Young Adult Zoonoses Hospitals, University statistics & numerical data Leishmaniasis, Visceral epidemiology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: French Transliterated Title: Étude de 71 cas de leishmaniose viscérale diagnostiqués au CHU Mustapha d'Alger entre 1998 et 2009. Publication Type: English Abstract; Journal Article Language: French [Med Mal Infect] 2012 Mar; Vol. 42 (3), pp. 119-25. <i>Date of Electronic Publication: </i>2012 Feb 16. MeSH Terms: Hospitals, University / statistics & numerical data ; Leishmaniasis, Visceral / epidemiology ; Adolescent ; Adult ; Age Distribution ; Aged ; Algeria / epidemiology ; Animals ; Antiprotozoal Agents / therapeutic use ; Bone Marrow / parasitology ; Child ; Child, Preschool ; Dog Diseases / epidemiology ; Dog Diseases / parasitology ; Dogs / parasitology ; Endemic Diseases ; Humans ; Infant ; Insect Vectors / parasitology ; Leishmania infantum / isolation & purification ; Leishmaniasis, Visceral / diagnosis ; Leishmaniasis, Visceral / transmission ; Leishmaniasis, Visceral / veterinary ; Middle Aged ; Phlebotomus / parasitology ; Retrospective Studies ; Sex Distribution ; Young Adult ; Zoonoses Substance Nomenclature: 0 (Antiprotozoal Agents) Entry Date(s): Date Created: 20120221 Date Completed: 20120724 Latest Revision: 20120326 Update Code: 20231215

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