Long-term efficacy of goniosynechialysis combined with phacoemulsification for primary angle closure.
In: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, Jg. 251 (2013-03-01), Heft 3, S. 825-30
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Zugriff:
Aims: To evaluate long-term efficacy of goniosynechialysis (GSL) combined with phacoemulsification and intraocular lens implantation (phaco-GSL) for primary angle closure or primary angle-closure glaucoma (PAC/PACG) and to analyze risk factors for surgical outcomes.
Methods: We reviewed medical records of 109 eyes of 109 patients (mean [± SD] age 70 ± 9.4 years) who underwent phaco-GSL as primary treatment of PAC/PACG at five institutions. All eyes had a preoperative intraocular pressure (IOP) of ≥ 21 mmHg with or without medications. Surgical failure was defined as: (1) condition A: persistent IOP values of ≥ 21 mmHg, or (2) condition B: IOP values of ≥ 18 mmHg, with or without topical ocular medication, at two consecutive follow-up visits, or additional operations needed. Risk factors for surgical failure were analyzed via Cox proportional hazards model.
Results: Mean follow-up was 40.0 months (range, 1 to 139 months). Probabilities of treatment success at 1 and 3 years after phaco-GSL were 85.9 % and 85.9 % (condition A) and 66.2 % and 61.0 % (condition B) respectively. Via multivariable analysis, we identified risk factors for surgical failure to be younger age (relative risk [RR] = 0.93/year, P = 0.0333) and absence of postoperative laser peripheral iridoplasty (LPI) (P = 0.0359) for condition A, and younger age (RR = 0.94/year, P = 0.0035), lower preoperative IOP (RR = 0.93/mm Hg, P = 0.0131), and absence of postoperative LPI (RR = 2.34, P = 0.0228) for condition B.
Conclusions: The outcome of phaco-GSL for PAC/PACG may depend on age, preoperative IOP, and postoperative LPI.
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Long-term efficacy of goniosynechialysis combined with phacoemulsification for primary angle closure.
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Autor/in / Beteiligte Person: | Kameda, T ; Inoue, T ; Inatani, M ; Tanihara, H |
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Zeitschrift: | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, Jg. 251 (2013-03-01), Heft 3, S. 825-30 |
Veröffentlichung: | Berlin ; New York : Springer-Verlag, c1982-, 2013 |
Medientyp: | academicJournal |
ISSN: | 1435-702X (electronic) |
DOI: | 10.1007/s00417-012-2091-8 |
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