Almond "Appetizer" Effect on Glucose Tolerance Test (GTT) Results.

Crouch, MA ; Slater RT 3rd

In: Journal of the American Board of Family Medicine : JABFM, Jg. 29 (2016-11-12), Heft 6, S. 759-766

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Background: The extent to which glucose intolerance can be acutely improved with dietary modification is unclear. The purpose of this study was to test the effect of ingesting a low-calorie almond preload ("appetizer") 30 minutes before oral glucose tolerance testing in glucose-intolerant individuals without diabetes.

Methods: Twenty adults with prediabetes or isolated 1-hour glucose ≥160 mg/dL underwent 2 fasting oral glucose tolerance tests (GTTs)-1 standard GTT and 1 GTT 30 minutes after eating a half ounce (12) of dry-roasted almonds. Fourteen participants met 1 or more prediabetes diagnostic criteria; 6 had only elevated 1-hour glucose ≥160 mg/dL.

Results: The mean 1-hour plasma glucose after the almond preload was 37.1 mg/dL (19.4%) lower (154.6 vs 191.7; P < .001) than in the standard GTT. The almond preload reduced the area under the glucose curve by 15.5% (P < .001). Eight individuals had a marked hypoglycemic effect (glucose reduced by 45 to 110 mg/dL); 4 had a moderate hypoglycemic effect (22-32 mg/dL).

Conclusion: A low-calorie almond "appetizer" showed promise as an option for decreasing postprandial hyperglycemia in individuals with prediabetes or isolated 1-hour postprandial hyperglycemia. Further study is needed to confirm and refine the role of such a premeal appetizer in the self-care of prediabetes.

Titel:	Almond "Appetizer" Effect on Glucose Tolerance Test (GTT) Results.
Autor/in / Beteiligte Person:	Crouch, MA ; Slater RT 3rd
Link:	Full Text Finder (Volltext)
Zeitschrift:	Journal of the American Board of Family Medicine : JABFM, Jg. 29 (2016-11-12), Heft 6, S. 759-766
Veröffentlichung:	Lexington, KY : American Board of Family Medicine, c2006-, 2016
Medientyp:	academicJournal
ISSN:	1558-7118 (electronic)
DOI:	10.3122/jabfm.2016.06.160128
Schlagwort:	Adult Aged Aged, 80 and over Cross-Over Studies Diet Therapy methods Fasting Female Glucose Intolerance blood Glucose Intolerance therapy Glucose Tolerance Test Humans Hyperglycemia blood Male Middle Aged Prediabetic State diet therapy Self Care methods Young Adult Blood Glucose analysis Glucose Intolerance diagnosis Nuts Prediabetic State blood Prunus dulcis
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Research Support, Non-U.S. Gov't Language: English [J Am Board Fam Med] 2016 Nov 12; Vol. 29 (6), pp. 759-766. MeSH Terms: Nuts* ; Prunus dulcis* ; Blood Glucose / analysis ; Glucose Intolerance / diagnosis ; Prediabetic State / *blood ; Adult ; Aged ; Aged, 80 and over ; Cross-Over Studies ; Diet Therapy / methods ; Fasting ; Female ; Glucose Intolerance / blood ; Glucose Intolerance / therapy ; Glucose Tolerance Test ; Humans ; Hyperglycemia / blood ; Male ; Middle Aged ; Prediabetic State / diet therapy ; Self Care / methods ; Young Adult Contributed Indexing: Keywords: Area Under Curve; Blood Glucose; Eating; Energy Intake; Fasting; Food Habits; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Prediabetic State; Prunus dulcis; Self-Care Substance Nomenclature: 0 (Blood Glucose) Entry Date(s): Date Created: 20170112 Date Completed: 20171116 Latest Revision: 20180827 Update Code: 20240513

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