Laser Peripheral Iridotomy versus Trabeculectomy as an Initial Treatment for Primary Angle-Closure Glaucoma.
In: Journal of ophthalmology, Jg. 2017 (2017), S. 2761301
Online
academicJournal
Zugriff:
Purpose: To compare laser peripheral iridotomy (LPI) with trabeculectomy as an initial treatment for primary angle-closure glaucoma (PACG) with peripheral anterior synechiae (PAS) ≥ 6 clock hours.
Methods: Patients were drawn from two randomized controlled trials. 38 eyes of 38 patients (PAS ≥ 6 clock hours) were treated with LPI (group 1) while 111 eyes of 111 PACG patients (PAS ≥ 6 clock hours) underwent primary trabeculectomy (group 2). All patients underwent a comprehensive ophthalmic examination at baseline and at postoperative visits and were followed up for a minimum of one year.
Results: Group 2 had higher baseline IOP (45.7 ± 14.8 mmHg versus 34.3 ± 14.3 mmHg) than group 1 and more clock hours of PAS (10.4 ± 1.9 versus 9.0 ± 2.2). IOPs at all postoperative visits were significantly lower in group 2 than in group 1 ( p = 0.000). Five eyes in group 1 required trabeculectomy. 17 of the 38 eyes in group 1 (44.7%) required IOP-lowering medications as compared to seven of the 111 eyes in group 2 (6.3%). Cataract progression was documented in 2 eyes (5.3%) in group 1 and 16 eyes (14.4%) in group 2.
Conclusions: Primary trabeculectomy for PACG (PAS ≥ 6 clock hours) is more effective than LPI in lowering IOP.
| Titel: |
Laser Peripheral Iridotomy versus Trabeculectomy as an Initial Treatment for Primary Angle-Closure Glaucoma.
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| Autor/in / Beteiligte Person: | Chen, YY ; Fan, SJ ; Liang, YB ; Rong, SS ; Meng, HL ; Wang, X ; Thomas, R ; Wang, NL |
| Link: | |
| Zeitschrift: | Journal of ophthalmology, Jg. 2017 (2017), S. 2761301 |
| Veröffentlichung: | New York, NY : Hindawi Publishing Corporation, 2017 |
| Medientyp: | academicJournal |
| ISSN: | 2090-004X (print) |
| DOI: | 10.1155/2017/2761301 |
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