Correction
There is an error in the last sentence of the Results section. The correct sentence is: However, Fig 2D shows there was no muscle damage, and a very slight macrophage infiltrations when Allo was administered.
In Table 3, the values in the Ec row under columns GSH and T are incorrect. Please see the corrected Table 3 here.
null: Values of CK, Ur.Ac., Na+, K+, TBARS, GSH and body temperature (T).
CK Ur.Ac. Na+ K+ TBARS GSH T Sham 382±70 1.5±0.30 143.0±0.02 4.1±0.10 0.60±0.10 2.16±0.08 36.8±0.10 Ec 1473±22a 2.03±0.26 141.0±0.02 7.8±0.49 2.31±0.39 0.88±0.16 40.3±0.18 Ec+NAC 2355±48 2.80±0.06 139.3±2.5 8.60±0.10 0.89±0.10* 1.55±0.10* 39.4±1.05 NAC+Ec 2854±98 2.83±0.70 142.0±1.1 7.65±1.65 0.73±0.13* 1.49±0.10* 40.7±0.25 Ec+Allo 935±81** 0.28±0.05** 142.0±1.4 4.75±0.16** 1.50±0.18 2.30±0.13+ 36.3±0.09+
- 5 CK- U/L; K+ mEq/L; UrAc mg/dL; Temperature in C°;
1 a p<0.01 vs Sham
- 2 *p<0.02 vs Ec;
- 3 **p<0.05 vs Ec;
- 4 +p<0.001 vs Ec; for Ec n = 7; for others n = 4; for sham n = 6
1 de Bragança AC , Moreau RLM , de Brito T , Shimizu MHM , Canale D , de Jesus DA , et al . ( 2017 ) Ecstasy induces reactive oxygen species, kidney water absorption and rhabdomyolysis in normal rats. Effect of N-acetylcysteine and Allopurinol in oxidative stress and muscle fiber damage . PLoS ONE 12 ( 7 ): e0179199 . https://doi.org/10.1371/journal.pone.0179199 28678861
By Ana C. de Bragança; Regina L. M. Moreau; Thales de Brito; Maria H. M. Shimizu; Daniele Canale; Denise A. de Jesus; Ana M. G. Silva; Pedro H. Gois; Antonio C. Seguro and Antonio J. Magaldi
