Einzeltreffer — DigiBib

Primary Objective: Only a few objective prognostic markers are available for patients with disorders of consciousness (DoC). We assessed whether the magnitude of short-latency afferent inhibition (SAI) might be a useful predictor of responsiveness recovery and functional outcome in patients with DoC.

Research Design: We enrolled 40 patients with prolonged Minimally Conscious State (MCS) and Unresponsive Wakefulness Syndrome (UWS) in a longitudinal, observational study.

Methods and Procedures: Clinical features (including Coma Recovery Scale-Revised, CRS-R, and Glasgow Outcome Scale, GOS) and SAI were collected at the study entry and after 18 months from study inclusion, to assess a correlation between SAI and the clinical outcome.

Main Outcomes and Results: At the follow-up, 19 patients remained in their baseline condition, whereas 7 UWS evolved into MCS or emerged-from-MCS (EMCS), eight MCS evolved into EMCS, and two MCS- evolved into MCS+. Two UWS and one MCS+ died for cardiopulmonary complications. The patients who showed the highest GOS, the highest CRS-R and the lowest SAI strength at study entry, improved at the follow-up.

Conclusions: Our findings suggest that an objective and simple neurophysiologic measure as SAI strength could provide useful information to predict the outcome and the behavioral responsiveness of patients with DoC.

Titel:	Looking toward predicting functional recovery in disorders of consciousness: can sensorimotor integration help us?
Autor/in / Beteiligte Person:	Billeri, L ; Naro, A ; Leo, A ; Galletti, B ; Tomasello, P ; Manuli, A ; Andronaco, V ; Lauria, P ; Bramanti, A ; Calabrò, RS
Zeitschrift:	Brain injury, Jg. 33 (2019), Heft 3, S. 364-369
Veröffentlichung:	London : Informa Healthcare ; <i>Original Publication</i>: London ; New York : Taylor & Francis, c1987-, 2019
Medientyp:	academicJournal
ISSN:	1362-301X (electronic)
DOI:	10.1080/02699052.2018.1553309
Schlagwort:	Adult Aged Biomarkers Brain Injuries complications Female Follow-Up Studies Glasgow Outcome Scale Humans Longitudinal Studies Male Middle Aged Neural Inhibition Persistent Vegetative State psychology Persistent Vegetative State rehabilitation Prognosis Recovery of Function Consciousness Disorders psychology Consciousness Disorders rehabilitation
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Observational Study Language: English [Brain Inj] 2019; Vol. 33 (3), pp. 364-369. <i>Date of Electronic Publication: </i>2018 Dec 02. MeSH Terms: Consciousness Disorders / psychology ; Consciousness Disorders / rehabilitation ; Adult ; Aged ; Biomarkers ; Brain Injuries / complications ; Female ; Follow-Up Studies ; Glasgow Outcome Scale ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Neural Inhibition ; Persistent Vegetative State / psychology ; Persistent Vegetative State / rehabilitation ; Prognosis ; Recovery of Function Contributed Indexing: Keywords: MCS; Sensorimotor integration; UWS; disorders of consciousness; prognosis Substance Nomenclature: 0 (Biomarkers) Entry Date(s): Date Created: 20181204 Date Completed: 20200131 Latest Revision: 20200131 Update Code: 20231215

Klicken Sie ein Format an und speichern Sie dann die Daten oder geben Sie eine Empfänger-Adresse ein und lassen Sie sich per Email zusenden.

BibTeX Citavi, JabRef, u.a.
(Literaturverwaltung)

PDF kein Volltext!
(Merkzettel, Notizen)

RIS Endnote, Citavi u.a.
(Literaturverwaltung)

MODS
(XML zur Weiterverarbeitung)

oder

Wählen Sie das für Sie passende Zitationsformat und kopieren Sie es dann in die Zwischenablage, lassen es sich per Mail zusenden oder speichern es als PDF-Datei.

Gewünschter Zitations-Stil:

oder

Bitte prüfen Sie, ob die Zitation formal korrekt ist, bevor Sie sie in einer Arbeit verwenden. Benutzen Sie gegebenenfalls den "Exportieren"-Dialog, wenn Sie ein Literaturverwaltungsprogramm verwenden und die Zitat-Angaben selbst formatieren wollen.

Looking toward predicting functional recovery in disorders of consciousness: can sensorimotor integration help us?