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- Nachgewiesen in: MEDLINE
- Sprachen: English
- Publication Type: Journal Article
- Language: English
- [Acta Pharmacol Sin] 2020 Aug; Vol. 41 (8), pp. 1025-1032. <i>Date of Electronic Publication: </i>2020 Mar 16.
- MeSH Terms: Apoptosis / *drug effects ; Infarction, Middle Cerebral Artery / *drug therapy ; Inflammation / *drug therapy ; Neuroprotective Agents / *therapeutic use ; Sapogenins / *therapeutic use ; Sirtuin 1 / *metabolism ; Animals ; Blood-Brain Barrier / drug effects ; Male ; Matrix Metalloproteinase 9 / metabolism ; Mice, Inbred C57BL ; NF-kappa B p50 Subunit / metabolism ; Signal Transduction / drug effects ; Tight Junctions / metabolism ; Tumor Suppressor Protein p53 / metabolism ; Up-Regulation / drug effects
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- Contributed Indexing: Keywords: SIRT1; apoptosis; cerebral ischemia; cycloastragenol; neuroinflammation
- Substance Nomenclature: 0 (NF-kappa B p50 Subunit) ; 0 (Neuroprotective Agents) ; 0 (Sapogenins) ; 0 (Trp53 protein, mouse) ; 0 (Tumor Suppressor Protein p53) ; 147257-52-1 (Nfkb1 protein, mouse) ; EC 3.4.24.35 (Matrix Metalloproteinase 9) ; EC 3.4.24.35 (Mmp9 protein, mouse) ; EC 3.5.1.- (Sirt1 protein, mouse) ; EC 3.5.1.- (Sirtuin 1) ; X37D9F2L0V (cycloastragenol)
- Entry Date(s): Date Created: 20200324 Date Completed: 20210528 Latest Revision: 20210528
- Update Code: 20240513
- PubMed Central ID: PMC7471431
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