Synthesis of melatonin by the pineal modified photoreceptors of birds immunocytochemical localization of hydroxyindole-O-methyltransferase.
In: Biology of the cell, Jg. 64 (1988), Heft 1, S. 93-6
academicJournal
Zugriff:
Photoperiodic control of several biological rhythms is exerted through the inhibitory effect of light on melatonin synthesis in the pineal organ. Hydroxyindole-O-methyltransferase (HIO-MT), the last acting-enzyme in melatonin biosynthesis, constitutes a specific marker of melatoninergic cells. In the present study, an antibody directed against chicken HIOMT was affinity-purified and used to identify melatoninergic cells in the pineal organ of chicken, quail, sparrow and blackbird. Regardless of the species, intense immunocytochemical reactions were observed in modified photoreceptors, whereas other cellular constituents (mostly glial cells) remained unlabeled. We conclude that modified photoreceptors synthesize melatonin in the avian pineal gland and are thus accountable for the translation of the photoperiodic input into hormonal output.
| Titel: |
Synthesis of melatonin by the pineal modified photoreceptors of birds immunocytochemical localization of hydroxyindole-O-methyltransferase.
|
|---|---|
| Autor/in / Beteiligte Person: | Guerlotte, J ; Voisin, P ; Brisson, P ; Faure, JP ; Collin, JP |
| Link: | |
| Zeitschrift: | Biology of the cell, Jg. 64 (1988), Heft 1, S. 93-6 |
| Veröffentlichung: | 2012- : Chichester : Wiley-Blackwell ; <i>Original Publication</i>: Ivry sur Seine France : Publié par la Société française de microscopie électronique avec le concours du Centre national de la recherche scientifique et de l'Institute national de la santé et de la recherche médicale, [1981-, 1988 |
| Medientyp: | academicJournal |
| ISSN: | 0248-4900 (print) |
| DOI: | 10.1016/0248-4900(88)90098-6 |
| Schlagwort: |
|
| Sonstiges: |
|