Einzeltreffer — DigiBib

Purpose: Myopic vitreopathy features precocious fibrous vitreous liquefaction and early posterior vitreous detachment (PVD). It is unclear whether visual function is affected by myopic vitreopathy and PVD. This study assessed the relationships among axial length, structural vitreous density, PVD, and visual function.

Design: Retrospective case-control study.

Methods: Ultrasonography measurements were made of axial length, logMAR VA, contrast sensitivity function (CSF [Freiburg acuity contrast test]), and quantitative B-scan ultrasonography.

Results: Seventy-nine subjects (45 men and 34 women; mean age: 49 ± 14 years) were analyzed. Axial lengths ranged from 22 to 29.2 mm (mean: 24.9 ± 1.8 mm; myopic eyes: 26.35 ± 1.35 mm; and nonmyopic eyes: 23.45 ± 0.75 mm; P < .001). With increasing axial length there was greater vitreous echodensity (R: 0.573; P < .01) and degradation in CSF (R: 0.611; P < .01). Subgroup analyses found that myopic eyes (>- 3 diopters) had 37% more vitreous echodensity than nonmyopic eyes (762 ± 198 arbitrary units [AU] vs. 557 ± 171 AU, respectively; P < .001) and that CSF was 53% worse in myopic eyes (3.30 ± 1.24 Weber index [%W]) than in nonmyopic eyes (2.16 ± .59 %W; P < .001). Myopic eyes with PVD had 33% greater vitreous echodensity (815 ± 217 AU; P < .001) and 62% degradation in CSF (3.63 ± 2.99 %W) compared to nonmyopic eyes with PVD (613 ± 159 AU; 2.24 ± 0.69 %W; P < .001, each). Limited vitrectomy was performed in 11 of 40 cases (27.5%), normalizing vitreous echodensity and CSF in each case.

Conclusions: Axial myopia is associated with increased fibrous vitreous liquefaction and echodensity, as well as profound degradation of CSF. PVD in myopic eyes is associated with even more structural and functional abnormalities, normalized by limited vitrectomy. These findings may explain some common complaints of myopic patients with respect to vision and quality of life.

Titel:	Vitreous Structure and Visual Function in Myopic Vitreopathy Causing Vision-Degrading Myodesopsia.
Autor/in / Beteiligte Person:	Nguyen, JH ; Nguyen-Cuu, J ; Mamou, J ; Routledge, B ; Yee, KMP ; Sebag, J
Zeitschrift:	American journal of ophthalmology, Jg. 224 (2021-04-01), S. 246-253
Veröffentlichung:	1999- : New York, NY : Elsevier Science ; <i>Original Publication</i>: [Chicago, etc., Ophthalmic Pub. Co., etc.], 2021
Medientyp:	academicJournal
ISSN:	1879-1891 (electronic)
DOI:	10.1016/j.ajo.2020.09.017
Schlagwort:	Adult Aged Axial Length, Eye pathology Case-Control Studies Contrast Sensitivity physiology Eye Diseases diagnostic imaging Eye Diseases etiology Female Humans Male Middle Aged Retrospective Studies Tomography, Optical Coherence Ultrasonography Vitrectomy Vitreous Body diagnostic imaging Vitreous Detachment diagnostic imaging Vitreous Detachment etiology Eye Diseases physiopathology Myopia physiopathology Visual Acuity physiology Vitreous Body pathology Vitreous Detachment physiopathology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Research Support, Non-U.S. Gov't Language: English [Am J Ophthalmol] 2021 Apr; Vol. 224, pp. 246-253. <i>Date of Electronic Publication: </i>2020 Sep 17. MeSH Terms: Eye Diseases / physiopathology ; Myopia / physiopathology ; Visual Acuity / physiology ; Vitreous Body / pathology ; Vitreous Detachment / *physiopathology ; Adult ; Aged ; Axial Length, Eye / pathology ; Case-Control Studies ; Contrast Sensitivity / physiology ; Eye Diseases / diagnostic imaging ; Eye Diseases / etiology ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Tomography, Optical Coherence ; Ultrasonography ; Vitrectomy ; Vitreous Body / diagnostic imaging ; Vitreous Detachment / diagnostic imaging ; Vitreous Detachment / etiology Entry Date(s): Date Created: 20200920 Date Completed: 20210514 Latest Revision: 20210514 Update Code: 20231215

Klicken Sie ein Format an und speichern Sie dann die Daten oder geben Sie eine Empfänger-Adresse ein und lassen Sie sich per Email zusenden.

BibTeX Citavi, JabRef, u.a.
(Literaturverwaltung)

PDF kein Volltext!
(Merkzettel, Notizen)

RIS Endnote, Citavi u.a.
(Literaturverwaltung)

MODS
(XML zur Weiterverarbeitung)

oder

Wählen Sie das für Sie passende Zitationsformat und kopieren Sie es dann in die Zwischenablage, lassen es sich per Mail zusenden oder speichern es als PDF-Datei.

Gewünschter Zitations-Stil:

oder

Bitte prüfen Sie, ob die Zitation formal korrekt ist, bevor Sie sie in einer Arbeit verwenden. Benutzen Sie gegebenenfalls den "Exportieren"-Dialog, wenn Sie ein Literaturverwaltungsprogramm verwenden und die Zitat-Angaben selbst formatieren wollen.

Vitreous Structure and Visual Function in Myopic Vitreopathy Causing Vision-Degrading Myodesopsia.