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Aims: To investigate the association between B-type natriuretic peptide (BNP) and nocturia among community-dwelling males and females.

Methods: A total of 1096 participants (mean age 71.9 ± 7.1 years, 518 [47.2%] males) were included in the study. The number of nocturnal voids was recorded in a self-reported urination diary, and nocturia was defined as two or more voids per night. Daytime serum concentration of the N-terminal fragment of BNP precursor (NT-proBNP) was measured. Multivariable logistic regression analysis was performed to determine the association between NT-proBNP and nocturia.

Results: Nocturia was observed in 23.5% of females and 37.1% of males. Higher NT-proBNP (log pg/ml) was associated with nocturia in both gender groups (females: odds ratio [OR]: 1.67, 95% confidence interval [95% CI], 1.21-2.34, p = .002; males: OR: 1.26, 95% CI, 1.01-1.59, p = .046), independent of confounding variables including night-time blood pressure, mean voided volume, and chronic kidney disease. Although the increase in prevalence of nocturia with higher NT-proBNP was equivalent in both genders, some effect of gender on the relationship between NT-proBNP and nocturia was observed (p = .037). Nocturnal urine volume was also significantly and independently associated with NT-proBNP level (females: β = 32.9 ml, 95% CI, 5.63-60.2, p = .018; males: β = 34.6 ml, 95% CI, 9.40-59.9, p = .007).

Conclusions: This study revealed higher serum NT-proBNP is significantly and independently associated with the prevalence of nocturia in both males and females. This is an exploratory cross-sectional study and the analyses are post hoc, so further research works are needed to clarify the causality and clinical value.

Titel:	Association between NT-proBNP and nocturia among community-dwelling elderly males and females: A cross-sectional analysis of the HEIJO-KYO study.
Autor/in / Beteiligte Person:	Okumura, K ; Obayashi, K ; Tai, Y ; Yamagami, Y ; Negoro, H ; Kataoka, H ; Kurumatani, N ; Saeki, K
Link:	Full Text Finder (Volltext)
Zeitschrift:	Neurourology and urodynamics, Jg. 40 (2021), Heft 1, S. 112-119
Veröffentlichung:	New York : Alan R. Liss, c1982-, 2021
Medientyp:	academicJournal
ISSN:	1520-6777 (electronic)
DOI:	10.1002/nau.24550
Schlagwort:	Aged Biomarkers blood Cross-Sectional Studies Female Humans Independent Living Male Natriuretic Peptide, Brain blood Nocturia blood Peptide Fragments blood
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Research Support, Non-U.S. Gov't Language: English [Neurourol Urodyn] 2021 Jan; Vol. 40 (1), pp. 112-119. <i>Date of Electronic Publication: </i>2020 Oct 21. MeSH Terms: Natriuretic Peptide, Brain / blood ; Nocturia / blood ; Peptide Fragments / *blood ; Aged ; Biomarkers / blood ; Cross-Sectional Studies ; Female ; Humans ; Independent Living ; Male References: Hashim H, Blanker MH, Drake MJ, et al. International Continence Society (ICS) report on the terminology for nocturia and nocturnal lower urinary tract function. Neurourol Urodynam. 2019;38(2):499-508. https://doi.org/10.1002/nau.23917. ; Tikkinen KAO, Johnson TM, Tammela TLJ, et al. Nocturia frequency, bother, and quality of life: how often is too often? A population-based study in Finland. Eur Urol. 2010;57(3):488-498. https://doi.org/10.1016/j.eururo.2009.03.080. ; Bosch JLHR, Weiss JP. The prevalence and causes of nocturia. J Urology. 2010;184(2):440-446. https://doi.org/10.1016/j.juro.2010.04.011. ; Pesonen JS, Cartwright R, Vernooij RWM, et al. The impact of nocturia on mortality: a systematic review and meta-analysis. J Urology. 2019;203:486-495. https://doi.org/10.1097/ju.0000000000000463. ; Cornu J-N, Abrams P, Chapple CR, et al. A contemporary assessment of nocturia: definition, epidemiology, pathophysiology, and management-a systematic review and meta-analysis. Eur Urol. 2012;62(5):877-890. https://doi.org/10.1016/j.eururo.2012.07.004. ; Osman NI, Chapple CR, Wein AJ. Nocturia: current concepts and future perspectives. Acta Physiol. 2012;207(1):53-65. https://doi.org/10.1111/apha.12013. ; Vanderheyden M, Bartunek J, Goethals M. Brain and other natriuretic peptides: molecular aspects. Eur J Heart Fail. 2004;6(3):261-268. https://doi.org/10.1016/j.ejheart.2004.01.004. ; Cowie M. Clinical applications of B-type natriuretic peptide (BNP) testing. Eur Heart J. 2003;24(19):1710-1718. https://doi.org/10.1016/s0195-668x(03)00476-7. ; Weber M, Hamm C. Role of B-type natriuretic peptide (BNP) and NT-proBNP in clinical routine. Heart. 2006;92:843-849. https://doi.org/10.1136/hrt.2005.071233. ; Hildebrandt P, Collinson PO. Amino-terminal pro-B-type natriuretic peptide testing to assist the diagnostic evaluation of heart failure in symptomatic primary care patients. Am J Cardiol. 2008;101(3):S25-S28. https://doi.org/10.1016/j.amjcard.2007.11.016. ; Sugaya K, Nishijima S, Oda M, Owan T, Miyazato M, Ogawa Y. Biochemical and body composition analysis of nocturia in the elderly. Neurourol Urodynam. 2008;27(3):205-211. https://doi.org/10.1002/nau.20492. ; Miyazaki T, Kojima S, Yamamuro M, et al. Nocturia in patients with sleep-disordered breathing and cardiovascular disease. Circ J. 2015;79(12):2632-2640. https://doi.org/10.1253/circj.cj-15-0654. ; Yoshimura K, Nakayama T, Sekine A, et al. B-type natriuretic peptide as an independent correlate of nocturnal voiding in Japanese women. Neurourol Urodyn. 2012;31(8):1266-1271. https://doi.org/10.1002/nau.22250. ; Tabara Y, Matsumoto T, Murase K, et al. Lifestyle habits associated with nocturnal urination frequency: the Nagahama study. Neurourol Urodynam. 2019;38(8):2359-2367. https://doi.org/10.1002/nau.24156. ; Izumi K, Ito M, Inoue M, et al. MP31-05 impact of brain-type natriuretic peptide, a representative biomarker for cardiac load, on nocturia in men. J Urology. 2017;197(4S):e400. https://doi.org/10.1016/j.juro.2017.02.959. ; Obayashi K, Saeki K, Iwamoto J, et al. Positive effect of daylight exposure on nocturnal urinary melatonin excretion in the elderly: a cross-sectional analysis of the HEIJO-KYO study. J Clin Endocrinol Metab. 2012;97(11):4166-4173. https://doi.org/10.1210/jc.2012-1873. ; R Core Team. A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria; 2019. https://www.R-project.org/. ; Liu Y, Huang Z, Huang K, et al. The clinical value of N-terminal pro B-type natriuretic peptide in evaluating obstructive sleep apnea in patients with coronary artery disease. J Clin Sleep Med. 2019;15(10):1403-1409. https://doi.org/10.5664/jcsm.7962. ; Zhou J, Xia S, Li T, Liu R. Association between obstructive sleep apnea syndrome and nocturia: a meta-analysis. Sleep Breath. 2020:1-6. https://doi.org/10.1007/s11325-019-01981-6. ; Sadanaga T, Ando K, Hirota S, et al. B-type natriuretic peptide levels are decreased by reducing dietary salt intake in patients with compensated heart failure with preserved ejection fraction. Intern Med J. 2013;43(6):663-667. https://doi.org/10.1111/imj.12063. ; Okumura Y, Asai K, Kobayashi T, et al. Dietary sodium restriction reduces nocturnal urine volume and nocturnal polyuria index in renal allograft recipients with nocturnal polyuria. Urology. 2017;106:60-64. https://doi.org/10.1016/j.urology.2017.04.025. ; Matsuo T, Miyata Y, Sakai H. Effect of salt intake reduction on nocturia in patients with excessive salt intake. Neurourol Urodynam. 2019;38(3):927-933. https://doi.org/10.1002/nau.23929. ; Obayashi K, Saeki K, Kurumatani N. Independent associations between nocturia and nighttime blood pressure/dipping in elderly individuals: the HEIJO-KYO cohort. J Am Geriatr Soc. 2015;63(4):733-738. https://doi.org/10.1111/jgs.13333. ; Tabara Y, Igase M, Miki T, Ohyagi Y, Matsuda F, Kohara K. B-type natriuretic peptide is a determinant of the nocturnal increase in blood pressure independently of arterial hypertrophy and hypoxia. J Hypertens. 2016;34(12):2393-2401. https://doi.org/10.1097/hjh.0000000000001104. ; Obayashi K, Saeki K, Kurumatani N. Quantitative association between nocturnal voiding frequency and objective sleep quality in the general elderly population: the HEIJO-KYO cohort. Sleep Med. 2015;16(5):577-582. https://doi.org/10.1016/j.sleep.2015.01.021. Contributed Indexing: Keywords: aged; brain; community-based participatory research; natriuretic peptide; nocturia Substance Nomenclature: 0 (Biomarkers) ; 0 (Peptide Fragments) ; 0 (pro-brain natriuretic peptide (1-76)) ; 114471-18-0 (Natriuretic Peptide, Brain) Entry Date(s): Date Created: 20201021 Date Completed: 20210611 Latest Revision: 20210611 Update Code: 20231215

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Association between NT-proBNP and nocturia among community-dwelling elderly males and females: A cross-sectional analysis of the HEIJO-KYO study.