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This cohort study aimed to compare the incidence of type 2 diabetes in adults with depression-related weight gain, depression-related weight loss, depression with no weight change, and no depression. The study sample included 59,315 community-dwelling adults in Ontario, Canada. Depression-related weight change in the past 12 months was measured using the Composite International Diagnostic Interview-Short Form. Participants were followed for up to 20 years using administrative health data. Cox proportional hazards models compared the incidence of type 2 diabetes in adults with depression-related weight change and in adults with no depression. Adults with depression-related weight gain had an increased risk of type 2 diabetes compared to adults no depression (HR 1.70, 95% CI 1.32-2.20), adults with depression-related weight loss (HR 1.62, 95% CI 1.09-2.42), and adults with depression with no weight change (HR 1.39, 95% CI 1.03-1.86). Adults with depression with no weight change also had an increased risk of type 2 diabetes compared to those with no depression (HR 1.23, 95% CI 1.04-1.45). Associations were stronger among women and persisted after adjusting for attained overweight and obesity. Identifying symptoms of weight change in depression may aid in identifying adults at higher risk of type 2 diabetes and in developing tailored prevention strategies.

Titel:	Depression-related weight change and incident diabetes in a community sample.
Autor/in / Beteiligte Person:	Graham, E ; Watson, T ; Deschênes, SS ; Filion, KB ; Henderson, M ; Harper, S ; Rosella, LC ; Schmitz, N
Link:	View record at Springer (Volltext)
Zeitschrift:	Scientific reports, Jg. 11 (2021-06-30), Heft 1, S. 13575
Veröffentlichung:	London : Nature Publishing Group, copyright 2011-, 2021
Medientyp:	academicJournal
ISSN:	2045-2322 (electronic)
DOI:	10.1038/s41598-021-92963-w
Schlagwort:	Adolescent Adult Aged Cross-Sectional Studies Female Humans Incidence Male Middle Aged Ontario epidemiology Depression complications Depression epidemiology Diabetes Mellitus, Type 2 epidemiology Diabetes Mellitus, Type 2 etiology Obesity epidemiology Obesity etiology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Research Support, Non-U.S. Gov't Language: English [Sci Rep] 2021 Jun 30; Vol. 11 (1), pp. 13575. <i>Date of Electronic Publication: </i>2021 Jun 30. MeSH Terms: Depression* / complications ; Depression* / epidemiology ; Diabetes Mellitus, Type 2* / epidemiology ; Diabetes Mellitus, Type 2* / etiology ; Obesity* / epidemiology ; Obesity* / etiology ; Adolescent ; Adult ; Aged ; Cross-Sectional Studies ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Ontario / epidemiology References: Lancet Diabetes Endocrinol. 2018 Feb;6(2):122-129. (PMID: 29199115) ; Am J Clin Nutr. 2005 Mar;81(3):555-63. (PMID: 15755822) ; Diabetes Care. 2007 Dec;30(12):3105-9. (PMID: 17712026) ; BMC Public Health. 2013 Jan 09;13:16. (PMID: 23302258) ; Lancet. 2018 Nov 10;392(10159):1789-1858. (PMID: 30496104) ; Diabetes Res Clin Pract. 2010 Sep;89(3):309-19. (PMID: 20493574) ; Health Rep. 2008 Sep;19(3):71-82. (PMID: 18847148) ; JAMA. 2016 May 24-31;315(20):2230-2. (PMID: 27218634) ; J Nerv Ment Dis. 2006 Apr;194(4):235-40. (PMID: 16614543) ; Am J Epidemiol. 2017 May 1;185(9):734-742. (PMID: 28369312) ; Diabetes Care. 2011 Sep;34(9):1986-91. (PMID: 21775760) ; Brain Behav Immun. 2020 Jan;83:163-171. (PMID: 31604141) ; Diabetologia. 2010 Mar;53(3):467-71. (PMID: 20012009) ; Transl Psychiatry. 2019 Aug 20;9(1):193. (PMID: 31431611) ; J Affect Disord. 2014 Mar;156:156-63. (PMID: 24388685) ; J Affect Disord. 2020 Mar 15;265:224-232. (PMID: 32090745) ; Health Rep. 2009 Mar;20(1):53-8. (PMID: 19388369) ; PLoS One. 2017 Jul 31;12(7):e0182088. (PMID: 28759599) ; Ann Clin Psychiatry. 2007 Oct-Dec;19(4):257-64. (PMID: 18058283) ; Mol Psychiatry. 2020 Jul;25(7):1457-1468. (PMID: 29899546) ; Psychol Med. 2018 May;48(7):1102-1110. (PMID: 28889804) ; Mol Psychiatry. 2017 Jul;22(7):1026-1034. (PMID: 27725658) ; Int J Popul Data Sci. 2020 Mar 26;5(1):1155. (PMID: 34232968) ; Chronic Dis Can. 2000;21(2):68-72. (PMID: 11007657) ; Brain Behav Immun. 2020 Aug;88:174-183. (PMID: 32272220) ; Diabetes Care. 1992 Jul;15(7):815-9. (PMID: 1516497) ; J Affect Disord. 2014 Mar;156:92-103. (PMID: 24373526) ; Biol Psychiatry. 2020 Sep 1;88(5):369-380. (PMID: 32247527) ; Diabetes Care. 2015 Jul;38(7):1299-305. (PMID: 25852207) ; Am J Epidemiol. 2010 Aug 1;172(3):263-70. (PMID: 20603279) ; Obes Res. 2005 May;13(5):945-51. (PMID: 15919849) ; Epidemiol Psychiatr Sci. 2018 Feb;27(1):42-50. (PMID: 27784343) ; Diabetes Res Clin Pract. 2013 Nov;102(2):138-46. (PMID: 24139847) ; J Epidemiol Community Health. 2011 Jul;65(7):613-20. (PMID: 20515896) ; Psychosom Med. 2015 May;77(4):467-77. (PMID: 25867970) ; BMC Public Health. 2014 Feb 18;14:176. (PMID: 24548487) ; Diabetes Care. 2002 Mar;25(3):512-6. (PMID: 11874939) ; Brain Behav Immun. 2014 Oct;41:109-15. (PMID: 24838021) ; Lancet Diabetes Endocrinol. 2014 Mar;2(3):236-45. (PMID: 24622754) Grant Information: PCG-155452 Canada CIHR Entry Date(s): Date Created: 20210701 Date Completed: 20211108 Latest Revision: 20240402 Update Code: 20240402 PubMed Central ID: PMC8245524

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Depression-related weight change and incident diabetes in a community sample.