Correlation Analysis Between Ovarian Reserve and Thyroid Hormone Levels in Infertile Women of Reproductive Age.
In: Frontiers in endocrinology, Jg. 12 (2021-09-27), S. 745199
Online
academicJournal
Zugriff:
Objective: To analyze the correlation between ovarian reserve and thyroid function in women with infertility.
Methods: Retrospective analysis of the data of 496 infertility patients who visited the clinic between January 2019 and December 2020. According to the TSH level, it is grouped into <2.5 mIU/L, 2.5~4.0mIU/L and ≥4.0 mIU/L or according to the positive/negative thyroid autoimmune antibody. The relationship was assessed through the ovarian reserve, thyroid function, and anti-Müllerian hormone (AMH) levels in infertile patients. On the other hand, the patients are divided into groups according to age (≤29 years old, 30-34 years old and ≥35 years old), basic FSH (<10 IU/L and ≥10 IU/L), and AMH levels. The ovarian reserve was evaluated through the AMH and the antral follicle count (AFC).
Results: The average age of the patients was 30.31 ± 4.50 years old, and the average AMH level was 5.13 ± 4.30 ng/mL. 3.63% (18/496) of patients had abnormal TSH levels (normal: 0.35-5.5 mIU/L), the positive rate of thyroid peroxidase antibody (TPOAb) was 14.52% (72/496), the positive rate of anti-thyroglobulin antibody (TgAb) was 16.94% (84/496), and the positive rate of TPOAb and TgAb was 10.48% (52/496). After grouping according to TSH level or thyroid autoimmune antibody positive/negative grouping, the analysis found that there was no statistical significance in age, AMH level and basic FSH level among the groups (P>0.05). There were no significant differences in the levels of TSH, FT3, and FT4 among different ages, AMH, and FSH levels (P>0.05).
Conclusion: There is no significant correlation between ovarian reserve and thyroid function in infertile women.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2021 Wu, Zhao, Wang, Tang and Liu.)
Titel: |
Correlation Analysis Between Ovarian Reserve and Thyroid Hormone Levels in Infertile Women of Reproductive Age.
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Autor/in / Beteiligte Person: | Wu, J ; Zhao, YJ ; Wang, M ; Tang, MQ ; Liu, YF |
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Zeitschrift: | Frontiers in endocrinology, Jg. 12 (2021-09-27), S. 745199 |
Veröffentlichung: | [Lausanne : Frontiers Research Foundation], 2021 |
Medientyp: | academicJournal |
ISSN: | 1664-2392 (print) |
DOI: | 10.3389/fendo.2021.745199 |
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