| Sonstiges: |
- Nachgewiesen in: MEDLINE
- Sprachen: English
- Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- Language: English
- [Nat Neurosci] 2021 Nov; Vol. 24 (11), pp. 1601-1613. <i>Date of Electronic Publication: </i>2021 Oct 18.
- MeSH Terms: Adaptation, Physiological / *physiology ; Anhedonia / *physiology ; Dopaminergic Neurons / *metabolism ; Pain / *metabolism ; Ventral Tegmental Area / *metabolism ; Animals ; Conditioning, Operant / physiology ; Dopaminergic Neurons / chemistry ; Female ; Male ; Optogenetics / methods ; Pain / genetics ; Rats ; Rats, Long-Evans ; Rats, Transgenic ; Ventral Tegmental Area / chemistry
- References: Leknes, S. & Tracey, I. A common neurobiology for pain and pleasure. Nat. Rev. Neurosci. 9, 314–320 (2008). (PMID: 1835440010.1038/nrn2333) ; Bair, M. J., Robinson, R. L., Katon, W. & Kroenke, K. Depression and pain comorbidity: a literature review. Arch. Intern. Med. 163, 2433–2445 (2003). (PMID: 1460978010.1001/archinte.163.20.2433) ; McWilliams, L. A., Goodwin, R. D. & Cox, B. J. Depression and anxiety associated with three pain conditions: results from a nationally representative sample. Pain 111, 77–83 (2004). (PMID: 1532781110.1016/j.pain.2004.06.002) ; Campbell, L. C., Clauw, D. J. & Keefe, F. J. Persistent pain and depression: a biopsychosocial perspective. Biol. Psychiatry 54, 399–409 (2003). (PMID: 1289311410.1016/S0006-3223(03)00545-6) ; Volkow, N. D. & McLellan, A. T. Opioid abuse in chronic pain—misconceptions and mitigation strategies. N. Engl. J. Med. 374, 1253–1263 (2016). (PMID: 2702891510.1056/NEJMra1507771) ; Apkarian, A. V. et al. Chronic pain patients are impaired on an emotional decision-making task. Pain 108, 129–136 (2004). (PMID: 1510951610.1016/j.pain.2003.12.015) ; Verdejo-García, A., López-Torrecillas, F., Calandre, E. P., Delgado-Rodríguez, A. & Bechara, A. Executive function and decision-making in women with fibromyalgia. Arch. Clin. Neuropsychol. 24, 113–122 (2009). (PMID: 1939536110.1093/arclin/acp014) ; Wiech, K. et al. Influence of prior information on pain involves biased perceptual decision-making. Curr. Biol. 24, R679–R681 (2014). (PMID: 25093555412316110.1016/j.cub.2014.06.022) ; Seixas, D., Palace, J. & Tracey, I. Chronic pain disrupts the reward circuitry in multiple sclerosis. Eur. J. Neurosci. 44, 1928–1934 (2016). (PMID: 27178661) ; Nestler, E. J. & Carlezon, W. A. The mesolimbic dopamine reward circuit in depression. Biol. Psychiatry 59, 1151–1159 (2006). (PMID: 1656689910.1016/j.biopsych.2005.09.018) ; Schultz, W. Behavioral dopamine signals. Trends Neurosci. 30, 203–210 (2007). (PMID: 1740030110.1016/j.tins.2007.03.007) ; Berridge, K. C. & Robinson, T. E. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res. Rev. 28, 309–369 (1998). (PMID: 985875610.1016/S0165-0173(98)00019-8) ; Bromberg-Martin, E. S., Matsumoto, M. & Hikosaka, O. Dopamine in motivational control: rewarding, aversive, and alerting. Neuron 68, 815–834 (2010). (PMID: 21144997303299210.1016/j.neuron.2010.11.022) ; Martikainen, I. K. et al. Chronic back pain is associated with alterations in dopamine neurotransmission in the ventral striatum. J. Neurosci. 35, 9957–9965 (2015). (PMID: 26156996449524410.1523/JNEUROSCI.4605-14.2015) ; Scott, D. J., Heitzeg, M. M., Koeppe, R. A., Stohler, C. S. & Zubieta, J.-K. Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. J. Neurosci. 26, 10789–10795 (2006). (PMID: 17050717667476410.1523/JNEUROSCI.2577-06.2006) ; Benarroch, E. E. Involvement of the nucleus accumbens and dopamine system in chronic pain. Neurology 87, 1720–1726 (2016). (PMID: 2765573710.1212/WNL.0000000000003243) ; Hipolito, L. et al. Inflammatory pain promotes increased opioid self-administration: role of dysregulated ventral tegmental area opioid receptors. J. Neurosci. 35, 12217–12231 (2015). (PMID: 26338332455678710.1523/JNEUROSCI.1053-15.2015) ; Taylor, A. M. W. et al. Microglia disrupt mesolimbic reward circuitry in chronic pain. J. Neurosci. 35, 8442–8450 (2015). (PMID: 26041913445255210.1523/JNEUROSCI.4036-14.2015) ; Massaly, N. et al. Pain-induced negative affect is mediated via recruitment of the nucleus accumbens kappa opioid system. Neuron 102, 564–573.e6 (2019). (PMID: 30878290650900110.1016/j.neuron.2019.02.029) ; Schwartz, N. et al. Decreased motivation during chronic pain requires long-term depression in the nucleus accumbens. Science 345, 535–542 (2014). (PMID: 25082697421955510.1126/science.1253994) ; Matsui, A., Jarvie, B. C., Robinson, B. G., Hentges, S. T. & Williams, J. T. Separate GABA afferents to dopamine neurons mediate acute action of opioids, development of tolerance and expression of withdrawal. Neuron 82, 1346–1356 (2014). (PMID: 24857021407225610.1016/j.neuron.2014.04.030) ; Ozaki, S. et al. Suppression of the morphine-induced rewarding effect in the rat with neuropathic pain: implication of the reduction in µ-opioid receptor functions in the ventral tegmental area. J. Neurochem. 82, 1192–1198 (2002). (PMID: 1235876610.1046/j.1471-4159.2002.01071.x) ; Hodos, W. Progressive ratio as a measure of reward strength. Science 134, 943–944 (1961). (PMID: 1371487610.1126/science.134.3483.943) ; Brennan, K., Roberts, D. C., Anisman, H. & Merali, Z. Individual differences in sucrose consumption in the rat: motivational and neurochemical correlates of hedonia. Psychopharmacology (Berl.) 157, 269–276 (2001). (PMID: 10.1007/s002130100805) ; Kitai, S. T., Shepard, P. D., Callaway, J. C. & Scroggs, R. Afferent modulation of dopamine neuron firing patterns. Curr. Opin. Neurobiol. 9, 690–697 (1999). (PMID: 1060764910.1016/S0959-4388(99)00040-9) ; Neuhoff, H., Neu, A., Liss, B. & Roeper, J. I h channels contribute to the different functional properties of identified dopaminergic subpopulations in the midbrain. J. Neurosci. 22, 1290–1302 (2002). (PMID: 11850457675755810.1523/JNEUROSCI.22-04-01290.2002) ; Saddoris, M. P., Cacciapaglia, F., Wightman, R. M. & Carelli, R. M. Differential dopamine release dynamics in the nucleus accumbens core and shell reveal complementary signals for error prediction and incentive motivation. J. Neurosci. 35, 11572–11582 (2015). (PMID: 26290234454079610.1523/JNEUROSCI.2344-15.2015) ; Boekhoudt, L. et al. Enhancing excitability of dopamine neurons promotes motivational behaviour through increased action initiation. Eur. Neuropsychopharmacol. 28, 171–184 (2018). (PMID: 2915392810.1016/j.euroneuro.2017.11.005) ; Yang, H. et al. Nucleus accumbens subnuclei regulate motivated behavior via direct inhibition and disinhibition of VTA dopamine subpopulations. Neuron 97, 434–449.e4 (2018). (PMID: 29307710577338710.1016/j.neuron.2017.12.022) ; Al-Hasani, R. et al. Distinct subpopulations of nucleus accumbens dynorphin neurons drive aversion and reward. Neuron 87, 1063–1077 (2015). (PMID: 26335648462538510.1016/j.neuron.2015.08.019) ; Boender, A. J. et al. Combined use of the canine adenovirus-2 and DREADD-technology to activate specific neural pathways in vivo. PLoS ONE 9, e95392 (2014). (PMID: 24736748398819610.1371/journal.pone.0095392) ; Navratilova, E. et al. Pain relief produces negative reinforcement through activation of mesolimbic reward–valuation circuitry. Proc. Natl Acad. Sci. USA 109, 20709–20713 (2012). (PMID: 23184995352853410.1073/pnas.1214605109) ; Liu, M.-Y. et al. Sucrose preference test for measurement of stress-induced anhedonia in mice. Nat. Protoc. 13, 1686–1698 (2018). (PMID: 2998810410.1038/s41596-018-0011-z) ; van Zessen, R., Phillips, J. L., Budygin, E. A. & Stuber, G. D. Activation of VTA GABA neurons disrupts reward consumption. Neuron 73, 1184–1194 (2012). (PMID: 22445345331424410.1016/j.neuron.2012.02.016) ; Jhou, T. C., Fields, H. L., Baxter, M. G., Saper, C. B. & Holland, P. C. The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron 61, 786–800 (2009). (PMID: 19285474284147510.1016/j.neuron.2009.02.001) ; Huang, S., Borgland, S. L. & Zamponi, G. W. Peripheral nerve injury-induced alterations in VTA neuron firing properties. Mol. Brain 12, 89 (2019). (PMID: 31685030682725210.1186/s13041-019-0511-y) ; Creed, M. C., Ntamati, N. R. & Tan, K. R. VTA GABA neurons modulate specific learning behaviors through the control of dopamine and cholinergic systems. Front. Behav. Neurosci. 8, 8 (2014). (PMID: 24478655389786810.3389/fnbeh.2014.00008) ; Waung, M. W., Margolis, E. B., Charbit, A. R. & Fields, H. L. A midbrain circuit that mediates headache aversiveness in rats. Cell Rep. 28, 2739–2747.e4 (2019). (PMID: 31509737683108510.1016/j.celrep.2019.08.009) ; Schultz, W. Dopamine reward prediction error coding. Dialogues Clin. Neurosci. 18, 23–32 (2016). (PMID: 27069377482676710.31887/DCNS.2016.18.1/wschultz) ; Schultz, W., Dayan, P. & Montague, P. R. A neural substrate of prediction and reward. Science 275, 1593–1599 (1997). (PMID: 905434710.1126/science.275.5306.1593) ; Li, H. et al. Three rostromedial tegmental afferents drive triply dissociable aspects of punishment learning and aversive valence encoding. Neuron 104, 987–999.e4 (2019). (PMID: 31627985698909610.1016/j.neuron.2019.08.040) ; Morales, M. & Margolis, E. B. Ventral tegmental area: cellular heterogeneity, connectivity and behaviour. Nat. Rev. Neurosci. 18, 73–85 (2017). (PMID: 2805332710.1038/nrn.2016.165) ; Navratilova, E. & Porreca, F. Reward and motivation in pain and pain relief. Nat. Neurosci. 17, 1304–1312 (2014). (PMID: 25254980430141710.1038/nn.3811) ; Leknes, S., Lee, M., Berna, C., Andersson, J. & Tracey, I. Relief as a reward: hedonic and neural responses to safety from pain. PLoS ONE 6, e17870 (2011). (PMID: 21490964307238210.1371/journal.pone.0017870) ; Mohebi, A. et al. Dissociable dopamine dynamics for learning and motivation. Nature 570, 65–70 (2019). (PMID: 31118513655548910.1038/s41586-019-1235-y) ; Liu, S. et al. Neuropathic pain alters reward and affect via kappa opioid receptor (KOR) upregulation. FASEB J. https://doi.org/10.1096/fasebj.30.1_supplement.928.5 (2016). ; Hayward, M. D., Schaich-Borg, A., Pintar, J. E. & Low, M. J. Differential involvement of endogenous opioids in sucrose consumption and food reinforcement. Pharmacol. Biochem. Behav. 85, 601–611 (2006). (PMID: 17166571186843810.1016/j.pbb.2006.10.015) ; Nummenmaa, L. et al. μ-opioid receptor system mediates reward processing in humans. Nat. Commun. 9, 1500 (2018). (PMID: 29662095590258010.1038/s41467-018-03848-y) ; Harris, R. E. et al. Decreased central μ-opioid receptor availability in fibromyalgia. J. Neurosci. 27, 10000–10006 (2007). (PMID: 17855614667265010.1523/JNEUROSCI.2849-07.2007) ; Zhou, W. et al. A neural circuit for comorbid depressive symptoms in chronic pain. Nat. Neurosci. https://doi.org/10.1038/s41593-019-0468-2 (2019).
- Grant Information: R21 DA047127 United States DA NIDA NIH HHS; R21 DA041883 United States DA NIDA NIH HHS; R01 DA049924 United States DA NIDA NIH HHS; R21 DA042581 United States DA NIDA NIH HHS; R01 DA045463 United States DA NIDA NIH HHS; R01 DA042499 United States DA NIDA NIH HHS; F31 DA051124 United States DA NIDA NIH HHS; R33 DA041883 United States DA NIDA NIH HHS; R01 DA041781 United States DA NIDA NIH HHS
- Entry Date(s): Date Created: 20211019 Date Completed: 20211110 Latest Revision: 20240215
- Update Code: 20240215
- PubMed Central ID: PMC8556343
|
