Review of the Role of HER2/neu in Colorectal Carcinomas.
In: Cureus, Jg. 14 (2022-05-27), Heft 5, S. e25409
Online
academicJournal
Zugriff:
Human epidermal growth factor receptor 2 (HER2/neu) is an oncogenic driver and a proven target for treatment of breast and gastric cancers. The role of HER2/neu and its blockage in various tumors, particularly colorectal adenocarcinoma has been widely explored following the revolutionary impact of anti-HER2/neu therapy in breast and gastric carcinoma patients. This review aimed to highlight the most recent updates on the significance of HER2/neu as a prognostic and predictive factor in these tumors together with its subsequent possible therapeutic indications from preclinical tests and ongoing assessments testing anti-HER2/neu agents in colorectal carcinoma (CRC). In the near future with a growingly tailored therapeutic approach toward cancers, HER2/neu targeted therapeutic strategies may blend into CRC treatment methods.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Achalla et al.)
Titel: |
Review of the Role of HER2/neu in Colorectal Carcinomas.
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Autor/in / Beteiligte Person: | Achalla, LSV ; Shinde, RK ; Jogdand, S ; Vodithala, S |
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Zeitschrift: | Cureus, Jg. 14 (2022-05-27), Heft 5, S. e25409 |
Veröffentlichung: | Palo Alto, CA : Cureus, Inc., 2022 |
Medientyp: | academicJournal |
ISSN: | 2168-8184 (print) |
DOI: | 10.7759/cureus.25409 |
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