Sonstiges: |
- Nachgewiesen in: MEDLINE
- Sprachen: English
- Publication Type: Journal Article; Research Support, Non-U.S. Gov't
- Language: English
- [Synapse] 2022 Sep; Vol. 76 (11-12), pp. e22246. <i>Date of Electronic Publication: </i>2022 Jul 23.
- MeSH Terms: Cannabidiol* / metabolism ; Cannabidiol* / pharmacology ; Receptors, Cannabinoid* / metabolism ; Receptors, G-Protein-Coupled* / metabolism ; Receptors, Presynaptic* / metabolism ; Animals ; Azabicyclo Compounds ; Benzoates ; Bicuculline / pharmacology ; Calcium / metabolism ; Kainic Acid / metabolism ; Kainic Acid / pharmacology ; Neurotransmitter Agents / pharmacology ; RNA, Messenger / metabolism ; Rats ; Receptors, Dopamine D1 / metabolism ; Substance P / metabolism ; Substantia Nigra / metabolism ; Thapsigargin / metabolism ; Thapsigargin / pharmacology ; gamma-Aminobutyric Acid / metabolism
- References: Aceves, J., Floran, B., Sierra, A., & Mariscal, S. (1995). D-1 receptor mediated modulation of the release of gamma-aminobutyric acid by endogenous dopamine in the basal ganglia of the rat. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 19, 727-739. ; Alexander, G. E., & Crutcher, M. D. (1990). Functional architecture of basal ganglia circuits: Neural substrates of parallel processing. Trends in Neuroscience. (Tins), 13, 266-271. ; Alhouayek, M., Masquelier, J., & Muccioli, G. G. (2018). Lysophosphatidylinositols, from cell membrane constituents to GPR55 ligands. Trends in Pharmacological Sciences, 39, 586-604. ; Ari, I. L., Schwarz, L., & Atlas, D. (1989). Cholinergic-induced [3H] noradrenaline release in rat brain cortical slices is mediated via a pertussis toxin sensitive GTP binding protein and involves activation of protein kinase C. Cellular Signalling, 1, 461-470. ; Arias-Montano, J. A., Floran, B., Floran, L., Aceves, J., & Young, J. M. (2007). Dopamine D(1) receptor facilitation of depolarization-induced release of gamma-amino-butyric acid in rat striatum is mediated by the cAMP/PKA pathway and involves P/Q-type calcium channels. Synapse, 61, 310-319. ; Arizzi-LaFrance, M. N., Correa, M., Aragon, C. M., & Salamone, J. D. (2006). Motor stimulant effects of ethanol injected into the substantia nigra pars reticulata: Importance of catalase-mediated metabolism and the role of acetaldehyde. Neuropsychopharmacology, 31, 997-1008. ; Arnt, J., Scheel-Krüger, J., Magelund, G., & Krogsgaard-Larsen, P. (1979). Muscimol and related GABA receptor agonists: The potency of GABAergic drugs in vivo determined after intranigral injection. Journal of Pharmacy and Pharmacology, 31, 306-313. ; Balenga, N. A., Aflaki, E., Kargl, J., Platzer, W., Schroder, R., Blattermann, S., Kostenis, E., & Brown, A. J. (2011). GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. Cell Research, 21, 1452-1469. ; Barik, J., & Wonnacott, S. (2009). Molecular and cellular mechanisms of action of nicotine in the CNS. Handbook of Experimental Pharmacology, 173-207. ; Begg, M., Pacher, P., Batkai, S., Osei-Hyiaman, D., Offertaler, L., Mo, F. M., Liu, J., & Kunos, G. (2005). Evidence for novel cannabinoid receptors. Pharmacology & Therapeutics, 106, 133-145. ; Bisogno, T., Hanus, L., De Petrocellis, L., Tchilibon, S., Ponde, D. E., Brandi, I., Moriello, A. S., Davis, J. B., Mechoulam, R., & Di Marzo, V. (2001). Molecular targets for cannabidiol and its synthetic analogues: Effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. British Journal of Pharmacology, 134(4), 845-852. ; Brand, C. S., Hocker, H. J., Gorfe, A. A., Cavasotto, C. N., & Dessauer, C. W. (2013). Isoform selectivity of adenylyl cyclase inhibitors: Characterization of known and novel compounds. Journal of Pharmacology and Experimental Therapeutics, 347, 265-275. ; Brown, A. J., Castellano-Pellicena, I., Haslam, C. P., Nichols, P. L., & Dowell, S. J. (2018). Structure-activity relationship of the GPR55 antagonist, CID16020046. Pharmacology, 102, 324-331. ; Burnet, P., Eastwood, S., Lacey, K., & Harrison, P. (1995). The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain. Brain Research, 676, 157-168. ; Campos Campos, B., Avalos-Fuentes, A., Pina Leyva, C., Sanchez-Zavaleta, R., Loya-Lopez, S., Rangel-Barajas, C., Leyva-Gomez, G., & Cortes, H. (2020). Coexistence of D3 R typical and atypical signaling in striatonigral neurons during dopaminergic denervation. Correlation with D3 nf expression changes. Synapse, 74, e22152. ; Celorrio, M., Rojo-Bustamante, E., Fernandez-Suarez, D., Saez, E., Estella-Hermoso de Mendoza, A., Muller, C. E., Ramirez, M. J., & Oyarzabal, J. (2017). GPR55: A therapeutic target for Parkinson's disease? Neuropharmacology, 125, 319-332. ; Chanaday, N. L., & Kavalali, E. T. (2018). Presynaptic origins of distinct modes of neurotransmitter release. Current Opinion in Neurobiology, 51, 119-126. ; Chijiwa, T., Mishima, A., Hagiwara, M., Sano, M., Hayashi, K., Inoue, T., Naito, K., & Toshioka, T. (1990). Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide. (H-89) of PC12D pheochromocytoma cells. Journal of Biological Chemistry, 265, 5267-5272. ; Cortés, H., Paz, F., Erlij, D., Aceves, J., & Florán, B. (2010). GABAB receptors modulate depolarization-stimulated [3H] glutamate release in slices of the pars reticulata of the rat substantia nigra. European Journal of Pharmacology, 649, 161-167. ; Deliu, E., Sperow, M., Console-Bram, L., Carter, R. L., Tilley, D. G., Kalamarides, D. J., Kirby, L. G., & Brailoiu, G. C. (2015). The lysophosphatidylinositol receptor GPR55 modulates pain perception in the periaqueductal gray. Molecular Pharmacology, 88, 265-272. ; Deniau, J. M., Mailly, P., Maurice, N., & Charpier, S. (2007). The pars reticulata of the substantia nigra: A window to basal ganglia output. Progress in Brain Research, 160, 151-172. ; De Petrocellis, L., Orlando, P., Moriello, A. S., Aviello, G., Stott, C., Izzo, A. A., & Di Marzo, V. (2012). Cannabinoid actions at TRPV channels: Effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. Acta Physiol. (Oxf), 204(2), 255-266. ; Dessauer, C. W., Watts, V. J., Ostrom, R. S., Conti, M., Dove, S., & Seifert, R. (2017). International union of basic and clinical pharmacology. CI. Structures and small molecule modulators of mammalian adenylyl cyclases. Pharmacological Reviews, 69, 93-139. ; Doyle, T. B., Muntean, B. S., Ejendal, K. F., Hayes, M. P., Soto-Velasquez, M., Martemyanov, K. A., Dessauer, C. W., & Hu, C. D. (2019). Identification of novel adenylyl cyclase 5. (AC5) signaling networks in D1 and D2 medium spiny neurons using bimolecular fluorescence complementation screening. Cells, 8. ; Drzazga, A., Sowinska, A., Krzeminska, A., Rytczak, P., Koziolkiewicz, M., & Gendaszewska-Darmach, E. (2017). Lysophosphatidylcholine elicits intracellular calcium signaling in a GPR55-dependent manner. Biochemical and Biophysical Research Communications, 489, 242-247. ; Fan, P., Jiang, Z., Diamond, I., & Yao, L. (2009). Up-regulation of AGS3 during morphine withdrawal promotes cAMP superactivation via adenylyl cyclase 5 and 7 in rat nucleus accumbens/striatal neurons. Molecular Pharmacology, 76, 526-533. ; Filip, B., Haydeh Niazi, S., & Hans, N. (2003). Somatodendritic dopamine release in rat substantia nigra influences motor performance on the accelerating rod. Brain Research, 973, 81-91. ; Floran, B., Barajas, C., Floran, L., Erlij, D., & Aceves, J. (2002). Adenosine A1 receptors control dopamine D1-dependent [(3)H]GABA release in slices of substantia nigra pars reticulata and motor behavior in the rat. Neuroscience, 115, 743-751. ; Foster, S. R., Hauser, A. S., Vedel, L., Strachan, R. T., Huang, X. P., Gavin, A. C., Shah, S. D., & Nayak, A. P. (2019). Discovery of human signaling systems: Pairing peptides to G protein-coupled receptors. Cell, 179, 895-908. e821. ; Garcia, M., Floran, B., Arias-Montano, J. A., Young, J. M., & Aceves, J. (1997). Histamine H3 receptor activation selectively inhibits dopamine D1 receptor-dependent [3H]GABA release from depolarization-stimulated slices of rat substantia nigra pars reticulata. Neuroscience, 80, 241-249. ; Gerfen, C. R. (1988). Synaptic organization of the striatum. Journal of Electron Microscopy Technique, 10, 265-281. ; Gomes, F. V., Resstel, L. B., & Guimaraes, F. S. (2011). The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors. Psychopharmacology, 213(2-3), 465-473. ; Guatteo, E., Chung, K. K., Bowala, T. K., Bernardi, G., Mercuri, N. B., & Lipski, J. (2005). Temperature sensitivity of dopaminergic neurons of the substantia nigra pars compacta: Involvement of transient receptor potential channels. Journal of Neurophysiology, 94(5), 3069-3080. ; Halls, M. L., & Cooper, D. M. (2011). Regulation by Ca2+-signaling pathways of adenylyl cyclases. Cold Spring Harbor perspectives in biology, 3, a004143. ; Henstridge, C. M., Balenga, N. A., Schroder, J., Kargl, K., Platzer, L., & Martini, L. (2010). GPR55 ligands promote receptor coupling to multiple signalling pathways. British Journal of Pharmacology, 160(3), 604-614. ; Hurst, K., Badgley, C., Ellsworth, T., Bell, S., Friend, L., Prince, B., Welch, J., & Cowan, Z. (2017). A putative lysophosphatidylinositol receptor GPR55 modulates hippocampal synaptic plasticity. Hippocampus, 27, 985-998. ; Iwamoto, T., Okumura, S., Iwatsubo, K., Kawabe, J., Ohtsu, K., Sakai, I., Hashimoto, Y., & Izumitani, A. (2003). Motor dysfunction in type 5 adenylyl cyclase-null mice. Journal of Biological Chemistry, 278, 16936-16940. ; Jiang, L. I., Collins, J., Davis, R., Fraser, I. D., & Sternweis, P. C. (2008). Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII. Journal of Biological Chemistry, 283, 23429-23439. ; Jiang, L. I., Wang, J. E., & Sternweis, P. C. (2013). Regions on adenylyl cyclase VII required for selective regulation by the G13 pathway. Molecular Pharmacology, 83, 587-593. ; Jijon-Lorenzo, R., Caballero-Floran, I. H., Recillas-Morales, S., Cortes, H., Avalos-Fuentes, J. A., Paz-Bermudez, F. J., Erlij, D., & Floran, B. (2018). Presynaptic dopamine D2 receptors modulate [(3)H]GABA release at striatopallidal terminals via activation of PLC→IP3→calcineurin and inhibition of AC→cAMP→PKA signaling cascades. Neuroscience, 372, 74-86. ; Jin, W., Lo, T.-M., Loh, H. H., & Thayer, S. A. (1994). U73122 inhibits phospholipase C-dependent calcium mobilization in neuronal cells. Brain Research, 642, 237-243. ; Johns, D. G., Behm, D. J., Walker, D. J., Ao, Z., Shapland, E. M., Daniels, D. A., Riddick, M., & Dowell, S. (2007). The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. British Journal of Pharmacology, 152, 825-831. ; Kallendrusch, S., Kremzow, S., Nowicki, M., Grabiec, U., Winkelmann, R., Benz, A., Kraft, R., & Bechmann, I. (2013). The G protein-coupled receptor 55 ligand l-alpha-lysophosphatidylinositol exerts microglia-dependent neuroprotection after excitotoxic lesion. Glia, 61, 1822-1831. ; Kaplan, J. S., Stella, N., Catterall, W. A., & Westenbroek, R. E. (2017). Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome. Proceedings of the National Academy of Sciences of the United States of America, 114, 11229-11234. ; Kargl, J., Brown, A. J., Andersen, L., Dorn, G., Schicho, R., Waldhoer, M., & Heinemann, A. (2013). A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function. Journal of Pharmacology and Experimental Therapeutics, 346, 54-66. ; Kayadjanian, N., Menétrey, A., & Besson, M. J. (1997). Activation of muscarinic receptors stimulates GABA release in the rat globus pallidus. Synapse, 26, 131-139. ; Kelm, M. K., Criswell, H. E., & Breese, G. R. (2007). Calcium release from presynaptic internal stores is required for ethanol to increase spontaneous gamma-aminobutyric acid release onto cerebellum Purkinje neurons. Journal of Pharmacology and Experimental Therapeutics, 323, 356-364. ; Khvotchev, M., Lonart, G., & Südhof, T. (2000). Role of calcium in neurotransmitter release evoked by α-latrotoxin or hypertonic sucrose. Neuroscience, 101, 793-802. ; Lanfumey, L., & Hamon, M. (2000). Central 5-HT(1A) receptors: Regional distribution and functional characteristics. Nuclear Medicine and Biology, 27(5), 429-435. ; Laprairie, R. B., Bagher, A. M., Kelly, M. E., & Denovan-Wright, E. M. (2015). Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor. British Journal of Pharmacology, 172(20), 4790-4805. ; Lauckner, J. E., Jensen, J. B., Chen, H. Y., Lu, H. C., Hille, B., & Mackie, K. (2008). GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proceedings of the National Academy of Sciences of the United States of America, 105, 2699-2704. ; Li, K., Fichna, J., Schicho, R., Saur, D., Bashashati, M., Mackie, K., Li, Y., & Zimmer, A. (2013). A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. Neuropharmacology, 71, 255-263. ; Magen, I., Avraham, Y., Ackerman, Z., Vorobiev, L., Mechoulam, R., & Berry, E. M. (2010). Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation. British Journal of Pharmacology, 159(4), 950-957. ; Mango, D., Bonito-Oliva, A., Ledonne, A., Nistico, R., Castelli, V., Giorgi, M., Sancesario, G., & Fisone, G. (2014). Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions. Neuropharmacology, 76 Pt A:127-136. ; Marichal-Cancino, B. A., Fajardo-Valdez, A., Ruiz-Contreras, A. E., Mendez-Diaz, M., & Prospero-Garcia, O. (2017). Advances in the physiology of GPR55 in the central nervous system. Current Neuropharmacology, 15, 771-778. ; Marinelli, S., Di Marzo, V., Berretta, N., Matias, I., Maccarrone, M., Bernardi, G., & Mercuri, N. B. (2003). Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors. Journal of Neuroscience, 23(8), 3136-3144. ; Marinelli, S., Di Marzo, V., Florenzano, F., Fezza, F., Viscomi, M. T., van der Stelt, M., Bernardi, G., Molinari, M., Maccarrone, M., & Mercuri, N. B. (2007). N-arachidonoyl-dopamine tunes synaptic transmission onto dopaminergic neurons by activating both cannabinoid and vanilloid receptors. Neuropsychopharmacology, 32(2), 298-308. ; Martinez-Pinilla, E., Aguinaga, D., Navarro, G., Rico, A. J., Oyarzabal, J., Sanchez-Arias, J. A., Lanciego, J. L., & Franco, R. (2019). Targeting CB1 and GPR55 endocannabinoid receptors as a potential neuroprotective approach for Parkinson's disease. Molecular Neurobiology, 56, 5900-5910. ; Martinez-Pinilla, E., Reyes-Resina, I., Onatibia-Astibia, A., Zamarbide, M., Ricobaraza, A., Navarro, G., Moreno, E., & Dopeso-Reyes, I. G. (2014). CB1 and GPR55 receptors are co-expressed and form heteromers in rat and monkey striatum. Experimental Neurology, 261, 44-52. ; Martinez-Pinilla, E., Rico, A. J., Rivas-Santisteban, R., Lillo, J., Roda, E., Navarro, G., Lanciego, J. L., & Franco, R. (2020). Expression of GPR55 and either cannabinoid CB1 or CB2 heteroreceptor complexes in the caudate, putamen, and accumbens nuclei of control, parkinsonian, and dyskinetic non-human primates. Brain Structure & Function, 225, 2153-2164. ; Mathew, S. S., & Hablitz, J. J. (2008). Calcium release via activation of presynaptic IP3 receptors contributes to kainate-induced IPSC facilitation in rat neocortex. Neuropharmacology, 55, 106-116. ; McHugh, D., Page, J., Dunn, E., & Bradshaw, H. B., Delta(9). (2012). -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. British Journal of Pharmacology, 165(8), 2414-2424. ; McKillop, A. M., Moran, B. M., Abdel-Wahab, Y. H., & Flatt, P. R. (2013). Evaluation of the insulin releasing and antihyperglycaemic activities of GPR55 lipid agonists using clonal beta-cells, isolated pancreatic islets and mice. British Journal of Pharmacology, 170, 978-990. ; Meredith, G. E., & Kang, U. J. (2006). Behavioral models of Parkinson's disease in rodents: A new look at an old problem. Movement disorders, 21, 1595-1606. ; Mezey, E., Toth, Z. E., Cortright, D. N., Arzubi, M. K., Krause, J. E., Elde, R., Guo, A., & Blumberg, P. M. (2000). Distribution of mRNA for vanilloid receptor subtype 1. (VR1) and VR1-like immunoreactivity, in the central nervous system of the rat and human. Proceeding of the National Academy of Sciences of the United States of America, 97, 3655-3660. ; Misgeld, U., Drew, G., & Yanovsky, Y. (2007). Presynaptic modulation of GABA release in the basal ganglia. Progress in Brain Research, 160, 245-259. ; Mishima, K., Hayakawa, K., Abe, K., Ikeda, T., Egashira, N., Iwasaki, K., & Fujiwara, M. (2005). Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism. Stroke; A Journal of Cerebral Circulation, 36(5), 1077-1082. ; Mizuno, K., Kurokawa, K., & Ohkuma, S. (2013). Regulation of type 1 IP3 receptor expression by dopamine D2-like receptors via AP-1 and NFATc4 activation. Neuropharmacology, 71, 264-272. ; Momiyama, T., & Koga, E. (2001). Dopamine D(2)-like receptors selectively block N-type Ca(2+) channels to reduce GABA release onto rat striatal cholinergic interneurones. Journal of Physiology, 533, 479-492. ; Mons, N., Yoshimura, M., Ikeda, H., Hoffman, P. L., & Tabakoff, B. (1998). Immunological assessment of the distribution of type VII adenylyl cyclase in brain. Brain Research, 788, 251-261. ; Morales, P., & Reggio, P. H. (2017). An update on non-CB1, non-CB2 cannabinoid related G-protein-coupled receptors. Cannabis and Cannabinoid Research, 2, 265-273. ; Moreno, E., Andradas, C., Medrano, M., Caffarel, M. M., Perez-Gomez, E., Blasco-Benito, S., Gomez-Canas, M., & Pazos, M. R. (2014). Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling. Journal of Biological Chemistry, 289, 21960-21972. ; Musella, A., Fresegna, D., Rizzo, F. R., Gentile, A., Bullitta, S., De Vito, F., Guadalupi, L., & Centonze, D. (2017). A novel crosstalk within the endocannabinoid system controls GABA transmission in the striatum. Science Reports, 7, 7363. ; Nava-Asbell, C., Paz-Bermudez, F., Erlij, D., Aceves, J., & Floran, B. (2007). GABA(B) receptor activation inhibits dopamine D1 receptor-mediated facilitation of [(3)H]GABA release in substantia nigra pars reticulata. Neuropharmacology, 53, 631-637. ; Oka, S., Nakajima, K., Yamashita, A., Kishimoto, S., & Sugiura, T. (2007). Identification of GPR55 as a lysophosphatidylinositol receptor. Biochemical and Biophysical Research Communications, 362, 928-934. ; Paxinos, G., & Watson, C. (2006). The rat brain in stereotaxic coordinates: Hard cover edition. 6th edn. Academic Press. ; Pertwee, R. G. (2007). GPR55: A new member of the cannabinoid receptor clan? British Journal of Pharmacology, 152, 984-986. ; Pertwee, R. G., Howlett, A. C., Abood, M. E., Alexander, S. P., Di Marzo, V., Elphick, M. R., Greasley, P. J., Hansen, H. S., Kunos, G., Mackie, K., Mechoulam, R., & Ross, R. A. (2010). International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: Beyond CB(1) and CB(2). Pharmacological Reviews, 62(4), 588-631. ; Pieroni, J. P., Jacobowitz, O., Chen, J., & Iyengar, R. (1993a). Signal recognition and integration by Gs-stimulated adenylyl cyclases. Current Opinion in Neurobiology, 3, 345-351. ; Pieroni, J. P., Miller, D., Premont, R. T., & Iyengar, R. (1993b). Type 5 adenylyl cyclase distribution. Nature, 363, 679-680. ; Pietr, M., Kozela, E., Levy, R., Rimmerman, N., Lin, Y. H., Stella, N., Vogel, Z., & Juknat, A. (2009). Differential changes in GPR55 during microglial cell activation. Febs Letters, 583, 2071-2076. ; Piomelli, D. (2003). The molecular logic of endocannabinoid signalling. Nature Reviews Neuroscience, 4, 873-884. ; Qin, N., Neeper, M. P., Liu, Y., Hutchinson, T. L., Lubin, M. L., & Flores, C. M. (2008). TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. Journal of Neuroscience, 28(24), 6231-6238. ; Rangel-Barajas, C., Silva, I., Lopez-Santiago, L. M., Aceves, J., Erlij, D., & Floran, B. (2011). L-DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V/VI and increased GABA release in the substantia nigra reticulata. Neurobiology of Disease, 41, 51-61. ; Recillas-Morales, S., Sanchez-Vega, L., Ochoa-Sanchez, N., Caballero-Floran, I., Paz-Bermudez, F., Silva, I., Aceves, J., Erlij, D., & Florán, B. (2014). L-type Ca(2)(+) channel activity determines modulation of GABA release by dopamine in the substantia nigra reticulata and the globus pallidus of the rat. Neuroscience, 256, 292-301. ; Riad, M., Garcia, S., Watkins, K. C., Jodoin, N., Doucet, E., Langlois, X., el Mestikawy, S., Hamon, M., & Descarries, L. (2000). Somatodendritic localization of 5-HT1A and preterminal axonal localization of 5-HT1B serotonin receptors in adult rat brain. Journal of Comparative Neurology, 417(2), 181-194. ; Robertson-Gray, O. J., Walsh, S. K., Ryberg, E., Jonsson-Rylander, A. C., Lipina, C., & Wainwright, C. L. (2019). l-alpha-Lysophosphatidylinositol. (LPI) aggravates myocardial ischemia/reperfusion injury via a GPR55/ROCK-dependent pathway. Pharmacology Research and Perspectives, 7, e00487. ; Rodriguez-Sanchez, M., Escartin-Perez, R. E., Leyva-Gomez, G., Avalos-Fuentes, J. A., Paz-Bermudez, F. J., Loya-Lopez, S. I., Aceves, J., & Erlij, D. (2019). Blockade of intranigral and systemic D3 receptors stimulates motor activity in the rat promoting a reciprocal interaction among glutamate, dopamine, and GABA. Biomolecules, 9. ; Ross, R. A. (2009). The enigmatic pharmacology of GPR55. Trends in Pharmacological Sciences, 30, 156-163. ; Russo, E. B., Burnett, A., Hall, B., & Parker, K. K. (2005). Agonistic properties of cannabidiol at 5-HT1a receptors. Neurochemical Research, 30, 1037-1043. ; Ryberg, E., Larsson, N., Sjogren, S., Hjorth, S., Hermansson, N. O., Leonova, J., Elebring, T., & Nilsson, K. (2007). The orphan receptor GPR55 is a novel cannabinoid receptor. British Journal of Pharmacology, 152, 1092-1101. ; Sadana, R., & Dessauer, C. W. (2009). Physiological roles for G protein-regulated adenylyl cyclase isoforms: Insights from knockout and overexpression studies. Neuro-Signals, 17, 5-22. ; Sakmann, B. (2006). Patch pipettes are more useful than initially thought: Simultaneous pre- and postsynaptic recording from mammalian CNS synapses in vitro and in vivo. Pflugers Archiv: European Journal of Physiology, 453, 249-259. ; Sanabra, C., & Mengod, G. (2011). Neuroanatomical distribution and neurochemical characterization of cells expressing adenylyl cyclase isoforms in mouse and rat brain. Journal of Chemical Neuroanatomy, 41, 43-54. ; Sanchez-Zavaleta, R., Cortes, H., Avalos-Fuentes, J. A., Garcia, U., Segovia Vila, J., Erlij, D., & Floran, B. (2018). Presynaptic cannabinoid CB2 receptors modulate [(3) H]-Glutamate release at subthalamo-nigral terminals of the rat. Synapse, 72, e22061. ; Schroder, R., Janssen, N., Schmidt, J., Kebig, A., Merten, N., Hennen, S., Muller, A., & Blattermann, S. (2010). Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements. Nature Biotechnology, 28, 943-949. ; Schwarcz, R., & Coyle, J. T. (1977). Striatal lesions with kainic acid: Neurochemical characteristics. Brain Research, 127, 235-249. ; Senarath, K., Kankanamge, D., Samaradivakara, S., Ratnayake, K., Tennakoon, M., & Karunarathne, A. (2018). Regulation of G protein betagamma signaling. International Review of Cell and Molecular Biology, 339, 133-191. ; Sharir, H., & Abood, M. E. (2010). Pharmacological characterization of GPR55, a putative cannabinoid receptor. Pharmacology & Therapeutics, 126(3), 301-313. ; Smith, Y., & Bolam, J. P. (1989). Neurons of the substantia nigra reticulata receive a dense GABA-containing input from the globus pallidus in the rat. Brain Research, 493, 160-167. ; Stehno-Bittel, L., Krapivinsky, G., Krapivinsky, L., Perez-Terzic, C., & Clapham, D. E. (1995). The G protein beta gamma subunit transduces the muscarinic receptor signal for Ca2+ release in Xenopus oocytes. Journal of Biological Chemistry, 270, 30068-30074. ; Stromberg, I., & Bickford-Wimer, P. (1991). Effects of locally applied D1 and D2 agonists on striatal neurons with 6-OHDA and pertussis toxin lesions. Brain Research, 564, 279-285. ; Sylantyev, S., Jensen, T. P., Ross, R. A., & Rusakov, D. A. (2013). Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses. Proceedings of the National Academy of Sciences of the United States of America, 110, 5193-5198. ; Trevitt, J., Carlson, B., Correa, M., Keene, A., Morales, M., & Salamone, J. (2002). Interactions between dopamine D1 receptors and γ-aminobutyric acid mechanisms in substantia nigra pars reticulata of the rat: Neurochemical and behavioral studies. Psychopharmacology, 159, 229-237. ; Vong, C. T., Tseng, H. H. L., Kwan, Y. W., Lee, S. M., & Hoi, M. P. M. (2019). G-protein coupled receptor 55 agonists increase insulin secretion through inositol trisphosphate-mediated calcium release in pancreatic beta-cells. European Journal of Pharmacology, 854, 372-379. ; Voorn, P., Gerfen, C. R., & Groenewegen, H. J. (1989). Compartmental organization of the ventral striatum of the rat: Immunohistochemical distribution of enkephalin, substance P, dopamine, and calcium-binding protein. Journal of Comparative Neurology, 289, 189-201. ; Wallmichrath, I., & Szabo, B. (2002). Cannabinoids inhibit striatonigral GABAergic neurotransmission in the mouse. Neuroscience, 113, 671-682. ; Wang, J., Lu, H. X., & Wang, J. (2019). Cannabinoid receptors in osteoporosis and osteoporotic pain: A narrative update of review. Journal of Pharmacy and Pharmacology, 71, 1469-1474. ; Watkins, A. R. (2019). Cannabinoid interactions with ion channels and receptors. Channels. (Austin), 13, 162-167. ; Whyte, L. S., Ryberg, E., Sims, N. A., Ridge, S. A., Mackie, K., Greasley, P. J., Ross, R. A., & Rogers, M. J. (2009). The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo. Proceedings of the National Academy of Sciences of the United States of America, 106, 16511-16516. ; Wu, C. S., Chen, H., Sun, H., Zhu, J., Jew, C. P., Wager-Miller, J., Straiker, A., & Spencer, C. (2013). GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. PLoS One, 8, e60314. ; Yang, H., Zhou, J., & Lehmann, C. (2016). GPR55 - a putative “type 3” cannabinoid receptor in inflammation. Journal of Basic and Clinical Physiology and Pharmacology, 27, 297-302. ; Yoshimura, M., Ikeda, H., & Tabakoff, B. (1996). mu-Opioid receptors inhibit dopamine-stimulated activity of type V adenylyl cyclase but enhance dopamine-stimulated activity of type VII adenylyl cyclase. Molecular Pharmacology, 50, 43-51. ; Young, L. H., Balin, B. J., & Weis, M. T. (2005). Go 6983: A fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury. Cardiovascular Drug Reviews, 23, 255-272. ; Zanelati, T. V., Biojone, C., Moreira, F. A., Guimaraes, F. S., & Joca, S. R. (2010). Antidepressant-like effects of cannabidiol in mice: Possible involvement of 5-HT1A receptors. British Journal of Pharmacology, 159(1), 122-128.
- Contributed Indexing: Keywords: GRR55 receptors; LPI; cannabinoids; motor behavior; substantia nigra
- Substance Nomenclature: 0 (4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid) ; 0 (Azabicyclo Compounds) ; 0 (Benzoates) ; 0 (GPR55 protein, rat) ; 0 (Neurotransmitter Agents) ; 0 (RNA, Messenger) ; 0 (Receptors, Cannabinoid) ; 0 (Receptors, Dopamine D1) ; 0 (Receptors, G-Protein-Coupled) ; 0 (Receptors, Presynaptic) ; 19GBJ60SN5 (Cannabidiol) ; 33507-63-0 (Substance P) ; 56-12-2 (gamma-Aminobutyric Acid) ; 67526-95-8 (Thapsigargin) ; SIV03811UC (Kainic Acid) ; SY7Q814VUP (Calcium) ; Y37615DVKC (Bicuculline)
- Entry Date(s): Date Created: 20220713 Date Completed: 20220920 Latest Revision: 20221011
- Update Code: 20231215
|