Case report: Triple whammy: Synchronous radiotherapy induced glioblastoma multiforme and papillary thyroid cancer following nasopharyngeal carcinoma.
In: Frontiers in oncology, Jg. 12 (2022-11-14), S. 1012395
Online
report
Zugriff:
Secondary malignancies following radiotherapy are well documented, with an estimated incidence of 5%. These may manifest as carcinomas, gliomas, or sarcomas within the previous radiation field. Glioblastoma multiforme following radiotherapy for nasopharyngeal carcinoma is an uncommon occurrence and carries a poor prognosis, whereas papillary thyroid carcinoma following radiotherapy is well documented, though the exact incidence is not well documented. The occurrence of synchronous radiotherapy-induced malignancy over both sites has not been described in the literature before. We describe a middle-aged gentleman diagnosed with glioblastoma multiforme and papillary thyroid carcinoma 6 years after radiotherapy for nasopharyngeal carcinoma. Though our case is the first reported case of a synchronous tumour of its nature, it is likely that such cases are under-reported. Long-term vigilance for loco-regional radiotherapy-induced secondary malignancies is a must, and the presence of a second distinct secondary malignancy must be entertained.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2022 Palaniandy, Kamarudin, Wong, Mohamed Mukari, Jiau and Bakar.)
Titel: |
Case report: Triple whammy: Synchronous radiotherapy induced glioblastoma multiforme and papillary thyroid cancer following nasopharyngeal carcinoma.
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Autor/in / Beteiligte Person: | Palaniandy, K ; Kamarudin, Z ; Wong, YP ; Mohamed Mukari, SA ; Jiau, WXH ; Bakar, AA |
Link: | |
Zeitschrift: | Frontiers in oncology, Jg. 12 (2022-11-14), S. 1012395 |
Veröffentlichung: | [Lausanne : Frontiers Research Foundation], 2022 |
Medientyp: | report |
ISSN: | 2234-943X (print) |
DOI: | 10.3389/fonc.2022.1012395 |
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