MIP-on-a-chip: Artificial receptors on microfluidic platforms for biomedical applications.

Karasu, T ; Özgür, E ; et al.

In: Journal of pharmaceutical and biomedical analysis, Jg. 226 (2023-03-20), S. 115257

academicJournal

Lab-on-a-chip (LOC) as an alternative biosensing approach concerning cost efficiency, parallelization, ergonomics, diagnostic speed, and sensitivity integrates the techniques of various laboratory operations such as biochemical analysis, chemical synthesis, or DNA sequencing, etc. on miniaturized microfluidic single chips. Meanwhile, LOC tools based on molecularly imprinted biosensing approach permit their applications in various fields such as medical diagnostics, pharmaceuticals, etc., which are user-, and eco-friendly sensing platforms for not only alternative to the commercial competitor but also on-site detection like point-of-care measurements. In this review, we focused our attention on compiling recent pioneer studies that utilized those intriguing methodologies, the microfluidic Lab-on-a-chip and molecularly imprinting approach, and their biomedical applications.

Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Titel:	MIP-on-a-chip: Artificial receptors on microfluidic platforms for biomedical applications.
Autor/in / Beteiligte Person:	Karasu, T ; Özgür, E ; Uzun, L
Zeitschrift:	Journal of pharmaceutical and biomedical analysis, Jg. 226 (2023-03-20), S. 115257
Veröffentlichung:	<2006->: London : Elsevier Science ; <i>Original Publication</i>: Oxford ; New York : Pergamon Press, c1983-, 2023
Medientyp:	academicJournal
ISSN:	1873-264X (electronic)
DOI:	10.1016/j.jpba.2023.115257
Schlagwort:	Microfluidics Point-of-Care Systems Lab-On-A-Chip Devices Receptors, Artificial Biosensing Techniques Microfluidic Analytical Techniques
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Review Language: English [J Pharm Biomed Anal] 2023 Mar 20; Vol. 226, pp. 115257. <i>Date of Electronic Publication: </i>2023 Jan 16. MeSH Terms: Receptors, Artificial* ; Biosensing Techniques* ; Microfluidic Analytical Techniques* ; Microfluidics ; Point-of-Care Systems ; Lab-On-A-Chip Devices Contributed Indexing: Keywords: Lab-on-a-chip (LOC); Microfluidic platforms; Molecularly imprinted polymers (MIP); Point-of-care (PoC) application; Real-time measurement Substance Nomenclature: 0 (Receptors, Artificial) Entry Date(s): Date Created: 20230120 Date Completed: 20230223 Latest Revision: 20230223 Update Code: 20231215

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