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Background: A bidirectional functional link between vestibular and fear-related disorders has been previously suggested.

Objective: To test a potential overlap of vestibular and fear systems with regard to their brain imaging representation maps.

Methods: By use of voxel-based mapping permutation of subject images, we conducted a meta-analysis of earlier functional magnetic resonance imaging (fMRI) studies applying vestibular stimulation and fear conditioning in healthy volunteers.

Results: Common clusters of concordance of vestibular stimulation and fear conditioning were found in the bilateral anterior insula cortex, ventrolateral prefrontal cortex and the right temporal pole, bilaterally in the adjacent ventrolateral prefrontal cortex, cingulate gyrus, secondary somatosensory cortex, superior temporal and intraparietal lobe, supplementary motor area and premotor cortex, as well as subcortical areas, such as the bilateral thalamus, mesencephalic brainstem including the collicular complex, pons, cerebellar vermis and bilateral cerebellar hemispheres. Peak areas of high concordance for activations during vestibular stimulation but deactivations during fear conditioning were centered on the posterior insula and S2.

Conclusions: The structural overlap of both networks allows the following functional interpretations: first, the amygdala, superior colliculi, and antero-medial thalamus might represent a release of preprogramed sensorimotor patterns of approach or avoidance. Second, the activation (vestibular system) and deactivation (fear system) of the bilateral posterior insula is compatible with the view that downregulation of the fear network by acute vestibular disorders or unfamiliar vestibular stimulation makes unpleasant perceived body accelerations less distressing. This also fits the clinical observation that patients with bilateral vestibular loss suffer from less vertigo-related anxiety.

Titel:	Common neural correlates of vestibular stimulation and fear learning: an fMRI meta-analysis.
Autor/in / Beteiligte Person:	Neumann, N ; Fullana, MA ; Radua, J ; Brandt, T ; Dieterich, M ; Lotze, M
Link:	View record at Springer (Volltext)
Zeitschrift:	Journal of neurology, Jg. 270 (2023-04-01), Heft 4, S. 1843-1856
Veröffentlichung:	Berlin ; New York, Springer-Verlag, 2023
Medientyp:	academicJournal
ISSN:	1432-1459 (electronic)
DOI:	10.1007/s00415-023-11568-7
Schlagwort:	Humans Brain Mapping Cerebral Cortex Temporal Lobe Brain Magnetic Resonance Imaging methods Fear
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Meta-Analysis; Journal Article Language: English [J Neurol] 2023 Apr; Vol. 270 (4), pp. 1843-1856. <i>Date of Electronic Publication: </i>2023 Feb 01. MeSH Terms: Magnetic Resonance Imaging* / methods ; Fear* ; Humans ; Brain Mapping ; Cerebral Cortex ; Temporal Lobe ; Brain References: Ann N Y Acad Sci. 2015 Apr;1343:10-26. (PMID: 25581203) ; J Comp Neurol. 2005 Dec 5;493(1):154-66. (PMID: 16254997) ; Brain Struct Funct. 2022 Apr;227(3):779-791. (PMID: 34611776) ; Science. 2005 Apr 15;308(5720):416-9. (PMID: 15831760) ; Mol Psychiatry. 2016 Apr;21(4):500-8. (PMID: 26122585) ; Neuroimage. 2008 Oct 1;42(4):1508-18. (PMID: 18644454) ; J Neurol. 2009 Jan;256(1):58-65. (PMID: 19221849) ; Neuroimage. 2013 Dec;83:75-86. (PMID: 23800791) ; PLoS One. 2009 Jun 10;4(6):e5865. (PMID: 19517024) ; J Neurol. 2008 Mar;255(3):420-8. (PMID: 18338198) ; Trends Neurosci. 1998 Jun;21(6):254-9. (PMID: 9641538) ; J Neurol Neurosurg Psychiatry. 2016 Apr;87(4):367-72. (PMID: 25886779) ; Ann N Y Acad Sci. 1999 May 28;871:293-312. (PMID: 10372080) ; Proc Biol Sci. 2011 May 22;278(1711):1476-81. (PMID: 20980303) ; J Physiol. 1990 Nov;430:537-57. (PMID: 2086773) ; Brain. 1996 Feb;119 ( Pt 1):101-10. (PMID: 8624674) ; Neuroimage. 2019 Feb 1;186:174-184. (PMID: 30389629) ; Handb Clin Neurol. 2019;166:39-51. (PMID: 31731924) ; Nat Rev Neurosci. 2015 Jun;16(6):317-31. (PMID: 25991441) ; Brain Res. 2004 Jan 16;996(1):126-37. (PMID: 14670639) ; J Cogn Neurosci. 2002 Apr 1;14(3):420-9. (PMID: 11970801) ; J Vestib Res. 2017;27(4):191-208. (PMID: 29036855) ; Eur J Neurol. 2021 May;28(5):1774-1778. (PMID: 33270346) ; J Neurophysiol. 2001 Feb;85(2):886-99. (PMID: 11160520) ; J Neurol Neurosurg Psychiatry. 2015 Mar;86(3):302-8. (PMID: 24963122) ; Biol Mood Anxiety Disord. 2012 Mar 08;2:6. (PMID: 22737993) ; Neuroimage. 2005 Jul 1;26(3):721-32. (PMID: 15955481) ; Neuroimage. 2016 Aug 1;136:94-105. (PMID: 27153979) ; Neurology. 2006 Mar 14;66(5):711-7. (PMID: 16534108) ; Neuropeptides. 2019 Aug;76:101934. (PMID: 31130301) ; Neuroimage. 2012 Mar;60(1):162-9. (PMID: 22209784) ; Brain. 1998 Sep;121 ( Pt 9):1749-58. (PMID: 9762962) ; J Anxiety Disord. 2001 Jan-Apr;15(1-2):53-79. (PMID: 11388358) ; Curr Opin Neurol. 2019 Feb;32(1):154-164. (PMID: 30461462) ; Brain Struct Funct. 2019 Dec;224(9):3001-3018. (PMID: 31451898) ; Psychophysiology. 2008 Mar;45(2):205-15. (PMID: 17995911) ; Ann N Y Acad Sci. 2011 Apr;1225:72-82. (PMID: 21534994) ; J Neurophysiol. 2007 Feb;97(2):1633-41. (PMID: 17135476) ; Neurosci Biobehav Rev. 2019 Jul;102:430-431. (PMID: 29886178) ; Cerebellum. 2022 Oct;21(5):791-800. (PMID: 35414040) ; Cereb Cortex. 2010 Nov;20(11):2636-46. (PMID: 20154013) ; Acta Otolaryngol. 2020 Aug;140(8):682-686. (PMID: 32401101) ; Neurology. 2014 Jun 10;82(23):2120-6. (PMID: 24814847) ; Front Psychiatry. 2014 Feb 10;5:13. (PMID: 24575054) ; Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G847-54. (PMID: 23494122) ; Exp Brain Res. 2015 Jan;233(1):237-52. (PMID: 25300959) ; Neuron. 1998 May;20(5):947-57. (PMID: 9620699) ; Eur Psychiatry. 2012 Nov;27(8):605-11. (PMID: 21658917) ; Cereb Cortex. 2011 Jul;21(7):1498-506. (PMID: 21097516) ; Ann N Y Acad Sci. 2009 May;1164:472-5. (PMID: 19645951) ; Neuroimage. 2007 Jul 1;36(3):511-21. (PMID: 17499520) ; Curr Opin Neurol. 2017 Feb;30(1):107-113. (PMID: 28002123) ; Neuroimage. 2022 Apr 15;250:118925. (PMID: 35074504) ; J Neurophysiol. 2018 Sep 1;120(3):1438-1450. (PMID: 29995604) ; Brain Res Cogn Brain Res. 2001 Dec;12(3):441-9. (PMID: 11689304) ; J Neurophysiol. 2012 May;107(10):2686-91. (PMID: 22378173) ; J Neurol. 2019 Sep;266(Suppl 1):89-92. (PMID: 31073714) ; Front Neurol. 2018 Jun 06;9:406. (PMID: 29928252) ; Brain Struct Funct. 2016 Apr;221(3):1291-308. (PMID: 25552315) ; Neuroimage. 2021 Feb 1;226:117588. (PMID: 33249212) ; Hum Brain Mapp. 2002 Jun;16(2):92-103. (PMID: 11954059) ; Proc Natl Acad Sci U S A. 2019 May 14;116(20):10122-10129. (PMID: 31028140) ; PLoS One. 2020 May 15;15(5):e0233262. (PMID: 32413079) ; Front Neuroanat. 2012 Apr 03;6:9. (PMID: 22514521) ; Hum Brain Mapp. 2009 Nov;30(11):3772-82. (PMID: 19492300) ; Am J Psychiatry. 2007 Oct;164(10):1476-88. (PMID: 17898336) ; Hum Brain Mapp. 2004 Dec;23(4):200-9. (PMID: 15449355) ; J Cogn Neurosci. 2014 Jan;26(1):16-27. (PMID: 23937691) ; Cereb Cortex. 2003 Sep;13(9):994-1007. (PMID: 12902399) ; Front Neural Circuits. 2012 Dec 11;6:96. (PMID: 23248584) ; J Neurophysiol. 2022 Apr 1;127(4):984-994. (PMID: 35235436) ; Curr Opin Neurol. 2020 Feb;33(1):136-141. (PMID: 31743237) ; Neuroimage. 2008 Jan 1;39(1):19-31. (PMID: 17919936) ; Brain Struct Funct. 2016 Jan;221(1):159-70. (PMID: 25269833) ; Neuroimage Clin. 2019;24:101942. (PMID: 31382239) ; Neuroscience. 2012 Jun 14;212:159-79. (PMID: 22516007) ; Neuroimage. 2018 Aug 1;176:550-553. (PMID: 29729389) ; Neurosci Biobehav Rev. 2017 Jun;77:247-285. (PMID: 28263758) ; Neuroimage. 2017 Sep;158:196-204. (PMID: 28669911) ; J Physiol. 2014 Aug 15;592(16):3671-85. (PMID: 24973412) ; Neuroimage. 2010 Jan 15;49(2):1760-8. (PMID: 19786103) ; J Neurol. 2020 Dec;267(Suppl 1):231-240. (PMID: 32444982) ; Nat Rev Neurosci. 2002 Aug;3(8):655-66. (PMID: 12154366) ; Neurosci Biobehav Rev. 2020 Dec;119:52-65. (PMID: 33011229) ; Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:310-321. (PMID: 30292730) ; Brain Struct Funct. 2013 Jan;218(1):255-67. (PMID: 22367249) Contributed Indexing: Keywords: Anxiety, fear conditioning; Functional magnetic resonance imaging; Vestibular system; Voxel-based meta-analysis Entry Date(s): Date Created: 20230201 Date Completed: 20230321 Latest Revision: 20230322 Update Code: 20231215 PubMed Central ID: PMC10025232

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Common neural correlates of vestibular stimulation and fear learning: an fMRI meta-analysis.