Einzeltreffer — DigiBib

Background: Season of birth has been associated with age at menarche. Maternal vitamin D levels in pregnancy may explain this effect. We investigated whether the season of first trimester or maternal 25-hydroxyvitamin D3 [25(OH)D3] levels were associated with pubertal timing in children.

Methods: We conducted a follow-up study of 15 819 children born in 2000-03 from the Puberty Cohort, nested in the Danish National Birth Cohort (DNBC). Mean differences in attaining numerous pubertal markers, including a combined estimate for the average age at attaining all pubertal markers, were estimated for low (November-April) relative to high (May-October) sunshine exposure season in the first trimester using multivariable interval-censored regression models. Moreover, we conducted a two-sample instrumental variable analysis using season as an instrument for maternal first-trimester 25(OH)D3 plasma levels obtained from a non-overlapping subset (n = 827) in the DNBC.

Results: For the combined estimate, girls and boys of mothers who had their first trimester during November-April had earlier pubertal timing than girls and boys of mothers whose first trimester occurred during May-October: -1.0 months (95% CI: -1.7 to -0.3) and -0.7 months (95% CI: -1.4 to -0.1), respectively. In the instrumental variable analysis, girls and boys also had earlier pubertal timing: respectively, -1.3 months (95% CI: -2.1 to -0.4) and -1.0 months (95% CI: -1.8 to -0.2) per SD (22 nmol/L) decrease in 25(OH)D3.

Conclusions: Both first pregnancy trimester during November-April and lower 25(OH)D3 were associated with earlier pubertal timing in girls and boys.

Titel:	The estimated effect of season and vitamin D in the first trimester on pubertal timing in girls and boys: a cohort study and an instrumental variable analysis.
Autor/in / Beteiligte Person:	Gaml-Sørensen, A ; Brix, N ; Ernst, A ; Lunddorf, LLH ; Lindh, C ; Toft, G ; Henriksen, TB ; Arah, OA ; Ramlau-Hansen, CH
Zeitschrift:	International journal of epidemiology, Jg. 52 (2023-10-05), Heft 5, S. 1328-1340
Veröffentlichung:	[London] Oxford University Press., 2023
Medientyp:	academicJournal
ISSN:	1464-3685 (electronic)
DOI:	10.1093/ije/dyad060
Schlagwort:	Male Child Pregnancy Female Humans Young Adult Adult Cohort Studies Pregnancy Trimester, First Follow-Up Studies Seasons Puberty Mothers Vitamins Vitamin D Prenatal Exposure Delayed Effects
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [Int J Epidemiol] 2023 Oct 05; Vol. 52 (5), pp. 1328-1340. MeSH Terms: Vitamin D* ; Prenatal Exposure Delayed Effects* ; Male ; Child ; Pregnancy ; Female ; Humans ; Young Adult ; Adult ; Cohort Studies ; Pregnancy Trimester, First ; Follow-Up Studies ; Seasons ; Puberty ; Mothers ; Vitamins References: Lancet Diabetes Endocrinol. 2016 Mar;4(3):254-264. (PMID: 26852256) ; J Biosoc Sci. 1992 Apr;24(2):167-73. (PMID: 1583031) ; Bone. 2012 Mar;50(3):605-10. (PMID: 22227435) ; Epidemiology. 1999 Jan;10(1):37-48. (PMID: 9888278) ; Sci Rep. 2020 Jan 17;10(1):555. (PMID: 31953469) ; Scand J Public Health. 2001 Dec;29(4):300-7. (PMID: 11775787) ; J Clin Endocrinol Metab. 2008 Mar;93(3):677-81. (PMID: 18089691) ; Biol Reprod. 2021 Apr 1;104(4):745-770. (PMID: 33354727) ; Epidemiology. 1995 Sep;6(5):520-4. (PMID: 8562629) ; Eur J Epidemiol. 2023 May;38(5):469-484. (PMID: 36952117) ; Pediatr Res. 2021 Jan;89(1):31-45. (PMID: 32353858) ; Reproduction. 2001 Aug;122(2):205-14. (PMID: 11467971) ; Hum Biol. 1970 Dec;42(4):570-80. (PMID: 5509690) ; Hum Reprod. 2005 Aug;20(8):2190-3. (PMID: 15890738) ; Int J Epidemiol. 2020 Apr 1;49(2):373-374g. (PMID: 31697338) ; Clin Chim Acta. 2015 Jun 15;446:175-80. (PMID: 25916694) ; Hum Reprod. 2004 Feb;19(2):445-7. (PMID: 14747195) ; Biochem Soc Trans. 2020 Aug 28;48(4):1725-1735. (PMID: 32779695) ; Sci Rep. 2015 Jun 18;5:11208. (PMID: 26084728) ; Mol Aspects Med. 2008 Dec;29(6):453-61. (PMID: 18786559) ; Heliyon. 2015 Oct 12;1(2):e00031. (PMID: 27123493) ; Arch Dis Child. 1969 Jun;44(235):291-303. (PMID: 5785179) ; Epidemiology. 2004 Sep;15(5):615-25. (PMID: 15308962) ; J Pediatr Endocrinol Metab. 2018 Jul 26;31(7):763-772. (PMID: 29953412) ; Nutrients. 2018 Nov 20;10(11):. (PMID: 30463277) ; Eur J Epidemiol. 2018 Jan;33(1):27-36. (PMID: 29349587) ; Am J Hum Biol. 2020 May;32(3):e23373. (PMID: 31837083) ; J Dev Orig Health Dis. 2021 Dec;12(6):849-858. (PMID: 33298226) ; J Clin Endocrinol Metab. 2020 Aug 1;105(8):. (PMID: 32179891) ; Clin Epidemiol. 2020 Jul 17;12:757-770. (PMID: 32765110) ; Environ Health Perspect. 2004 Jan;112(1):105-12. (PMID: 14698938) ; Am J Epidemiol. 2019 Jan 1;188(1):47-56. (PMID: 30239589) ; Stat Med. 2014 Jun 15;33(13):2297-340. (PMID: 24599889) ; J Clin Endocrinol Metab. 2010 Jan;95(1):263-70. (PMID: 19926714) ; Int J Epidemiol. 2000 Aug;29(4):722-9. (PMID: 10922351) ; Am J Hum Biol. 2020 Nov;32(6):e23417. (PMID: 32222094) ; Med Hypotheses. 2001 Mar;56(3):367-71. (PMID: 11359362) ; Arch Dis Child. 1970 Feb;45(239):13-23. (PMID: 5440182) ; Am J Hum Biol. 2016 Mar-Apr;28(2):226-32. (PMID: 26345586) ; Scand J Public Health. 2011 Jul;39(7 Suppl):22-5. (PMID: 21775345) ; Paediatr Perinat Epidemiol. 2020 Nov;34(6):668-677. (PMID: 32319135) ; Pediatrics. 2008 Feb;121 Suppl 3:S218-30. (PMID: 18245514) ; J Am Med Inform Assoc. 2015 Sep;22(5):1042-53. (PMID: 26041386) ; Pediatrics. 2009 May;123(5):e932-9. (PMID: 19403485) ; Paediatr Perinat Epidemiol. 2019 Jan;33(1):70-78. (PMID: 30307620) ; J Dev Orig Health Dis. 2014 Feb;5(1):2-15. (PMID: 24847686) ; Anthropol Anz. 2018 Aug 27;75(3):225-232. (PMID: 30058006) ; Arch Dis Child. 2011 Aug;96(8):703. (PMID: 21616960) ; Endocr Rev. 2003 Oct;24(5):668-93. (PMID: 14570750) Contributed Indexing: Keywords: 25-hydroxyvitamin D; Seasonal effect; delayed effects; fetal programming; instrumental variable analysis; maternal exposure; pregnancy season; prenatal exposure; pubertal development; vitamin D Substance Nomenclature: 1406-16-2 (Vitamin D) ; 0 (Vitamins) Entry Date(s): Date Created: 20230513 Date Completed: 20231127 Latest Revision: 20240428 Update Code: 20240428 PubMed Central ID: PMC11046010

Klicken Sie ein Format an und speichern Sie dann die Daten oder geben Sie eine Empfänger-Adresse ein und lassen Sie sich per Email zusenden.

BibTeX Citavi, JabRef, u.a.
(Literaturverwaltung)

PDF kein Volltext!
(Merkzettel, Notizen)

RIS Endnote, Citavi u.a.
(Literaturverwaltung)

MODS
(XML zur Weiterverarbeitung)

oder

Wählen Sie das für Sie passende Zitationsformat und kopieren Sie es dann in die Zwischenablage, lassen es sich per Mail zusenden oder speichern es als PDF-Datei.

Gewünschter Zitations-Stil:

oder

Bitte prüfen Sie, ob die Zitation formal korrekt ist, bevor Sie sie in einer Arbeit verwenden. Benutzen Sie gegebenenfalls den "Exportieren"-Dialog, wenn Sie ein Literaturverwaltungsprogramm verwenden und die Zitat-Angaben selbst formatieren wollen.

The estimated effect of season and vitamin D in the first trimester on pubertal timing in girls and boys: a cohort study and an instrumental variable analysis.