Clinicopathological Factors Influencing Resection Margin Involvement During Mohs Micrographic Surgery for Skin Tumors.

Chu, J ; Chung, Y ; et al.

In: Anticancer research, Jg. 43 (2023-06-01), Heft 6, S. 2707-2715

academicJournal

Background/aim: Mohs micrographic surgery (MMS) is a specialized procedure for removing skin tumors. Intraoperative assessment of the resection margin (RM) status using frozen section examination is a crucial component of MMS. This study aimed to identify significant clinicopathological characteristics that could help surgeons determine the optimal surgical extent.

Patients and Methods: One hundred and fifty-one patients with primary skin tumors were included. The relationship between RM involvement and the clinico-pathological characteristics was analyzed for each histological type.

Results: Basal cell carcinoma (BCC) was significantly more likely to exhibit positive RMs and required additional excision during MMS compared to squamous cell carcinoma. In addition, the probability of RM involvement was significantly higher in high-risk BCC subtypes.

Conclusion: When planning MMS, considering the histological type and presence of high-risk morphology may help surgeons perform more effective procedures.

Titel:	Clinicopathological Factors Influencing Resection Margin Involvement During Mohs Micrographic Surgery for Skin Tumors.
Autor/in / Beteiligte Person:	Chu, J ; Chung, Y ; Chae, SW ; Choi, YJ ; Kim, HS ; DO, SI
Zeitschrift:	Anticancer research, Jg. 43 (2023-06-01), Heft 6, S. 2707-2715
Veröffentlichung:	Attiki, Greece : International Institute of Anticancer Research ; <i>Original Publication</i>: Athens, Greece : Potamitis Press, 2023
Medientyp:	academicJournal
ISSN:	1791-7530 (electronic)
DOI:	10.21873/anticanres.16437
Schlagwort:	Humans Mohs Surgery methods Margins of Excision Neoplasm Recurrence, Local surgery Skin Neoplasms surgery Skin Neoplasms pathology Carcinoma, Basal Cell surgery Carcinoma, Basal Cell pathology Carcinoma, Squamous Cell surgery Carcinoma, Squamous Cell pathology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [Anticancer Res] 2023 Jun; Vol. 43 (6), pp. 2707-2715. MeSH Terms: Skin Neoplasms* / surgery ; Skin Neoplasms* / pathology ; Carcinoma, Basal Cell* / surgery ; Carcinoma, Basal Cell* / pathology ; Carcinoma, Squamous Cell* / surgery ; Carcinoma, Squamous Cell* / pathology ; Humans ; Mohs Surgery / methods ; Margins of Excision ; Neoplasm Recurrence, Local / surgery Contributed Indexing: Keywords: Mohs micrographic surgery; Skin; epidermal carcinoma; frozen section examination; resection margin involvement Entry Date(s): Date Created: 20230529 Date Completed: 20230531 Latest Revision: 20230531 Update Code: 20240514

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