Copper(II)/DBU Relay Catalyzed Annulation of α-Carbonyl-γ-alkynyl Sulfoxonium Ylides for Accessing N -Sulfonamido 2 H -Isoindoles.
In: Organic letters, Jg. 25 (2023-12-01), Heft 47, S. 8495-8500
academicJournal
Zugriff:
A copper(II)/DBU relay catalyzed annulation of α-carbonyl-γ-alkynyl sulfoxonium ylides as a new class of sulfoxonium ylide reagents with sulfonyl hydrazides is reported, enabling intramolecular oxygen migration to produce a series of N -sulfonamido 2 H -isoindoles with good yields. The present annulation proceeded readily by combining the Cu(II)-catalyzed 6- endo-dig oxo-cyclization with the DBU-catalyzed isochromene skeletal rearrangement, resulting in the formation of multiple new chemical bonds.
Titel: |
Copper(II)/DBU Relay Catalyzed Annulation of α-Carbonyl-γ-alkynyl Sulfoxonium Ylides for Accessing N -Sulfonamido 2 H -Isoindoles.
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Autor/in / Beteiligte Person: | Zhou, P ; Yang, WT ; Hao, WJ ; Jiang, B |
Zeitschrift: | Organic letters, Jg. 25 (2023-12-01), Heft 47, S. 8495-8500 |
Veröffentlichung: | Washington, DC : American Chemical Society, c1999-, 2023 |
Medientyp: | academicJournal |
ISSN: | 1523-7052 (electronic) |
DOI: | 10.1021/acs.orglett.3c03479 |
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