One year results of coronary bifurcation revascularization with the re-POT provisional sequential technique. The CABRIOLET registry.
In: International journal of cardiology, Jg. 397 (2024-02-15), S. 131632
academicJournal
Zugriff:
Background: Re-POT (proximal optimization technique (POT)) is a simple provisional sequential technique for percutaneous coronary bifurcation revascularization with better arterial geometry respect compared to classical techniques. Re-POT has demonstrated excellent mechanical and short-term clinical results. The multicenter CABRIOLET registry (NCT03550196) evaluate the long-term clinical benefit of the re-POT sequence in non-selected patients.
Methods: All consecutive patients presenting a coronary bifurcation lesion for which provisional stenting was indicated were included in 5 european centers. Re-POT strategy was systematically attempted. The primary endpoint was target lesion failure (TLF), comprising cardiac death, myocardial infarction, stent thrombosis and target lesion revascularization (TLR) at 12 months' follow-up. The secondary endpoints were the individual components of the primary endpoint, all-cause death, target vessel failure (TVF) and target vessel revascularization (TVR). Complex bifurcation was defined as Medina 0.1.1 or 1.1.1.
Results: A total of 500 patients aged 67.7 ± 11.7 years, 78.4% male, were included from 2015 to 2019, 174 of whom (34.8%) were considered having complex bifurcation lesions. Bifurcations involved the left main in 35.2% of cases. The full re-POT sequence was systematically performed in all cases. At 1 year, TLF was 2.0% (1.7% in complex vs. 2.1% in non-complex bifurcation; p = NS), and TLR was 1.6%, (1.1% vs. 1.8% respectively; p = NS). TVF and TVR rates were 3.2% and 2.8%. On multivariate analysis, only multivessel disease was predictive of TLF at 1 year (OR = 1.66 (1.09-2.53), p = 0.02).
Conclusions: In this large prospective all-comer registry, provisional stenting with re-POT technique appeared safe and effective at 1 year, without anatomical bifurcation restriction.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
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One year results of coronary bifurcation revascularization with the re-POT provisional sequential technique. The CABRIOLET registry.
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Autor/in / Beteiligte Person: | Dérimay, F ; Aminian, A ; Lattuca, B ; Souteyrand, G ; Maillard, L ; Alvain, S ; Cayla, G ; Motreff, P ; Bochaton, T ; Hayek, A ; Rioufol, G ; Finet, G |
Zeitschrift: | International journal of cardiology, Jg. 397 (2024-02-15), S. 131632 |
Veröffentlichung: | Amsterdam : Elsevier ; <i>Original Publication</i>: Amsterdam : Elsevier/North-Holland Biomedical Press, c1981-, 2024 |
Medientyp: | academicJournal |
ISSN: | 1874-1754 (electronic) |
DOI: | 10.1016/j.ijcard.2023.131632 |
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