Alteration of c-myc chromatin structure by avian leukosis virus integration.
In: Nature, Jg. 307 (1984-02-23), Heft 5953, S. 702-8
Online
academicJournal
Zugriff:
The most common sites of integration of the leukosis virus (ALV) long terminal repeat (LTR) in bursal lymphomas and derivative cell lines correspond to a region encompassed by two major hypersensitive sites in the 5' flanking region of the pre-integration, unrearranged c-myc gene. After integration of the ALV LTR, the major hypersensitive site within the avian c-myc oncogene region is within the proviral LTR, and the major hypersensitive sites normally found in uninfected cells 5' to the first c-myc coding exon are no longer detectable.
Titel: |
Alteration of c-myc chromatin structure by avian leukosis virus integration.
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Autor/in / Beteiligte Person: | Schubach, W ; Groudine, M |
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Zeitschrift: | Nature, Jg. 307 (1984-02-23), Heft 5953, S. 702-8 |
Veröffentlichung: | Basingstoke : Nature Publishing Group ; <i>Original Publication</i>: London, Macmillan Journals ltd., 1984 |
Medientyp: | academicJournal |
ISSN: | 0028-0836 (print) |
DOI: | 10.1038/307702a0 |
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