[The effect of the gas hypoxic mixture GHM-8 on the capacity of the stromal clonogenic cells (CFU-F) in rat bone marrow for postradiation recovery].
In: Radiobiologiia, Jg. 33 (1993-03-01), Heft 2, S. 244-54
academicJournal
Zugriff:
The effect of gas hypoxic mixture, containing 8% of O2 (GHM-8), on the ability of cell precursors of haemopoietic stroma (which form colonies (clones) of fibroblasts (CFU-F) in a culture, and are present in the bone marrow of adult rats) to repair potentially lethal and sublethal radiation damages has been investigated. The recovery of CFU-F from potentially lethal damages, that was studied after their delayed survival in a culture following irradiation of animals, proceeds at nearly the same rate in cells irradiated both in the air and in hypoxic conditions (GHM-8). Fractionated irradiation reduces the radioprotective effect of GHM-8 for CFU-F, particularly for the radioresistant subpopulation; the ability of CFU-F to recover from sublethal radiation damages decreases.
| Titel: |
[The effect of the gas hypoxic mixture GHM-8 on the capacity of the stromal clonogenic cells (CFU-F) in rat bone marrow for postradiation recovery].
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| Autor/in / Beteiligte Person: | Konopliannikov, AG ; Waĭnson, AA ; Kolesnikova, AI ; Zaĭtsev, VA ; SSh, Kal'sina ; Lepekhina, LA |
| Zeitschrift: | Radiobiologiia, Jg. 33 (1993-03-01), Heft 2, S. 244-54 |
| Veröffentlichung: | Moskva : Izdatelstvo Nauka ; <i>Original Publication</i>: Moskva, Izd-vo Akademiia nauk SSSR., 1993 |
| Medientyp: | academicJournal |
| ISSN: | 0033-8192 (print) |
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