Single-Center Experience With Lutonix Drug-Coated Balloons in Infrapopliteal Arteries.
In: Journal of Endovascular Therapy, Jg. 23 (2016-06-01), Heft 3, S. 417-423
academicJournal
Zugriff:
Purpose: To examine patient outcomes following the use of the Lutonix drug-coated balloon (DCB) in patients undergoing endovascular intervention in below-the-knee (BTK) arteries. Methods: A retrospective chart review identified 248 patients who were treated for symptomatic peripheral artery disease with the Lutonix DCB between May 2013 and October 2014. Forty patients were lost to follow-up, leaving 208 patients (mean age 74.1±9.7 years; 138 men) with evaluable data for outcome analysis. The patient cohort suffered from either severe claudication (38.6%) or critical limb ischemia (CLI; 61.4%) in 220 limbs. Almost two-thirds (140, 63.6%) of the 220 target lesions were total occlusions, and 37 (17.8%) of all patients had occlusion of all 3 BTK vessels before intervention. Results: Over a median 9-month follow-up, target lesion revascularization occurred in 15.9% of patients with an average time to first reintervention of 8 months. In total, 39 amputations were performed in 31 limbs. However, 17 of these amputations were preplanned minor amputations below the ankle; only 9 (4.1%) major amputations occurred corresponding to 6.6% of the CLI cohort. Freedom from the composite of death or major amputation was estimated as 92% and 85% at 6 and 12 months, respectively, by Kaplan-Meier analysis. In the full cohort, improvement of at least 1 Rutherford category was seen in 130 (59.1%) limbs after 1 year or at the last follow-up, with 104 (80.0%) of those limbs showing an improvement of ≥2 categories. Conclusion: From this single-center experience, the Lutonix DCB shows therapeutic promise in a disease state where new treatment options are needed. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Endovascular Therapy is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Single-Center Experience With Lutonix Drug-Coated Balloons in Infrapopliteal Arteries.
|
---|---|
Autor/in / Beteiligte Person: | Steiner, Sabine ; Schmidt, Andrej ; Bausback, Yvonne ; Bräunlich, Sven ; Ulrich, Matthias ; Banning-Eichenseer, Ursula ; Scheinert, Dierk |
Zeitschrift: | Journal of Endovascular Therapy, Jg. 23 (2016-06-01), Heft 3, S. 417-423 |
Veröffentlichung: | 2016 |
Medientyp: | academicJournal |
ISSN: | 1526-6028 (print) |
DOI: | 10.1177/1526602816645080 |
Schlagwort: |
|
Sonstiges: |
|