C-reactive protein can be an early predictor of postoperative complications after gastrectomy for gastric cancer.
In: Surgical Endoscopy & Other Interventional Techniques, Jg. 31 (2017), Heft 1, S. 445-454
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Zugriff:
Background: The clinical outcomes for postoperative complications (PCs) after gastrectomy depend on early diagnosis and intensive treatment. The aim of this study was to investigate the role of C-reactive protein (CRP) as an early predictor of PCs after gastrectomy for gastric cancer. Methods: A total of 334 consecutive patients who underwent gastrectomy for gastric cancer in 2014 were enrolled in this study. Blood samples were obtained preoperatively, and at postoperative days 1 and 4 for the measurement of inflammatory markers (white blood cell, neutrophil, and platelet counts, and CRP). Patients were classified into groups of major and minor/no PCs, which were defined as patients with PCs of more than grade III and those with grade I/II or without PCs, respectively, according to the Clavien-Dindo classification. Results: Twenty-five patients developed major PCs. The CRP on postoperative day 4 provided superior diagnostic accuracy in predicting major PCs compared to the other systematic inflammatory markers. Multivariate analysis identified a CRP level of 16.8 mg/dl or greater on postoperative day 4 as a significant predictive factor for major PCs. Conclusions: Among the various systemic inflammatory markers, CRP on postoperative day 4 is the most reliable predictor of PCs after gastrectomy for gastric cancer. [ABSTRACT FROM AUTHOR]
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C-reactive protein can be an early predictor of postoperative complications after gastrectomy for gastric cancer.
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Autor/in / Beteiligte Person: | Kim, Eun ; Park, Cho ; Song, Kyo ; Yim, Hyun ; Kim, Eun Young ; Yim, Hyun Woo ; Park, Cho Hyun ; Song, Kyo Young |
Zeitschrift: | Surgical Endoscopy & Other Interventional Techniques, Jg. 31 (2017), Heft 1, S. 445-454 |
Veröffentlichung: | 2017 |
Medientyp: | academicJournal |
ISSN: | 1866-6817 (print) |
DOI: | 10.1007/s00464-016-5272-4 |
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