Predicting Successful Recanalization in Patients with Native Coronary Chronic Total Occlusion: The Busan CTO Score.
In: Cardiology, Jg. 137 (2017-05-01), Heft 2, S. 83-91
Online
academicJournal
Zugriff:
Background: The optimal strategy to manage chronic total occlusion (CTO) remains unclear. The Japanese CTO multicenter registry (J-CTO) score is an established tool for predicting successful recanalization. However, it does not take into account nonangiographic predictors for final technique success. In the present study, we designed and tested a scoring model called the Busan single-center CTO registry (BCTO) score combining clinical and angiographic characteristics to predict successful CTO recanalization in Korean patients. Methods: Prospectively enrolled CTO patients ( n = 438) undergoing coronary intervention (1999-2015) were assessed. The B-CTO score comprises 6 independent predictors: age 60-74 years and lesion length ⩾ 20 mm were assigned 1 point each, while age ⩾ 75 years, female gender, lesion location in the right coronary artery, blunt stump and bending >45°were assigned 2 points each. For each predictor, the points assigned were based on the associated odds ratio by multivariate analysis. The lesions were classified into 4 groups according to the summation of points scored to assess the probability of successful CTO recanalization: easy (score 0-1), intermediate (score 2-3), difficult (score 4-5) and very difficult (score ⩾ 6). CTO opening was designated as the primary endpoint regardless of the interventional era or the skill of the operator. Results: The final success rate for BCTO was 81.1%. The probability of successful recanalization for patient groups classified as easy (n = 64), intermediate (n = 148), difficult (n = 134) and very difficult (n = 92) was 95.3, 86.5, 79.1 and 65.2%, respectively (p for trend <0.001). When compared to the J-CTO, the B-CTO score demonstrated a significant improvement in discrimination as indicated by the area under the receiver-operator characteristic curve (AUC 0.083; 95% CI 0.025-0.141), with a positive integrated discrimination improvement of 0.042 and a net reclassification improvement of 56.0%. Conclusions: The B-CTO score has been designed and validated in Korean patients with native coronary CTO and is an improved tool for predicting successful recanalization. Wider application of the B-CTO score remains to be explored. [ABSTRACT FROM AUTHOR]
Copyright of Cardiology is the property of Karger AG and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Predicting Successful Recanalization in Patients with Native Coronary Chronic Total Occlusion: The Busan CTO Score.
|
---|---|
Autor/in / Beteiligte Person: | Jin, Cai De ; Kim, Moo Hyun ; Kim, Soo Jin ; Lee, Kwang Min ; Kim, Tae Hyung ; Cho, Young-Rak ; Serebruany, Victor L. |
Link: | |
Zeitschrift: | Cardiology, Jg. 137 (2017-05-01), Heft 2, S. 83-91 |
Veröffentlichung: | 2017 |
Medientyp: | academicJournal |
ISSN: | 0008-6312 (print) |
DOI: | 10.1159/000455824 |
Schlagwort: |
|
Sonstiges: |
|