Congenital diaphragmatic hernia has a better prognosis when associated with a hernia sac.
In: Prenatal Diagnosis, Jg. 38 (2018-08-01), Heft 9, S. 638-644
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Zugriff:
Objective: To evaluate neonatal mortality and morbidity up to 6 months in neonates with congenital diaphragmatic hernia (CDH) with or without a hernia sac. Methods: Seventy-two cases of isolated CDH were included in a retrospective single-center study between January 2010 and December 2016. Hernia sac was defined at the time of surgery or at postmortem examination if the neonate died before surgery. Results: Seventeen newborns (23.6%) had a hernia sac. Survival at 6 months was significantly greater for isolated CDH with a hernia sac: 100% versus 63.6% (P = .003). High-frequency oscillatory ventilation was used significantly more in the no hernia sac group (P = .04). At surgery, the need for patch repair was significantly lower in the hernia sac group: 12% versus 50% (P = .005). The prenatal observed/expected lung-to-head ratio was significantly higher in the hernia sac group than in the no hernia sac group: 49.7% versus 38.6% (P < .05). Conclusion: The presence of a hernia sac in CDH is associated with better outcome, especially survival at 6 months. If the presence of a hernia sac is recognized as a particular entity, which carries a good prognosis, it is necessary to be able to diagnose it prenatally, especially in the era of prenatal fetal surgery. [ABSTRACT FROM AUTHOR]
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Congenital diaphragmatic hernia has a better prognosis when associated with a hernia sac.
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Autor/in / Beteiligte Person: | Bouchghoul, Hanane ; Marty, Oriane ; Fouquet, Virginie ; Cordier, Anne‐Gaël ; Senat, Marie‐Victoire ; Saada, Julien ; Mokhtari, Mostafa ; Le Sache, Nolwenn ; Martinovic, Jelena ; Benachi, Alexandra ; Cordier, Anne-Gaël ; Senat, Marie-Victoire |
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Zeitschrift: | Prenatal Diagnosis, Jg. 38 (2018-08-01), Heft 9, S. 638-644 |
Veröffentlichung: | 2018 |
Medientyp: | academicJournal |
ISSN: | 0197-3851 (print) |
DOI: | 10.1002/pd.5326 |
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