Transarterial Ethanol Ablation for Small Hepatocellular Carcinoma (≤ 3 cm): A Comparative Study Versus Radiofrequency Ablation.
In: CardioVascular & Interventional Radiology, Jg. 43 (2020-05-01), Heft 5, S. 732-739
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Zugriff:
Purpose: The objective was to evaluate the local treatment efficacy of transarterial ethanol ablation (TEA) as compared to radiofrequency ablation (RFA) for small hepatocellular carcinoma (HCC). Materials and Methods: This was a retrospective study between January 2005 and April 2017, in which the treatment outcomes of all patients who received either percutaneous TEA or RFA for HCC tumors of size ≤ 3 cm, of Child-Pugh grade A or B, received no prior treatment other than surgical resection, were compared. For TEA, a mixture of absolute ethanol and ethiodized oil at a proportion of 1:2 by volume was administered superselectively into the tumor via a microcatheter placed at the feeding arteries. The TEA group and the RFA group consisted of 68 consecutive patients (88 treated target tumors) and 129 consecutive patients (129 tumors), respectively. Results: Technical success was achieved in all the target tumors in both groups. Grade 3 complication (CIRSE Classification) of prolonged fever occurred in 3 cases with multi-focal and large tumors in the TEA group. There was no statistically significant difference in complete response rate between the TEA group (84/88 or 95.5%) and the RFA group (188/195 or 96.4%) (p = 0.7). Time to progression in the TEA group [median 11.9 months, interquartile range (IQR) 5.6-18 months] was not statistically different from that in the RFA group (median 9.5 months, IQR 3.5-18.7 months) (p = 0.773). Conclusion: TEA could be an effective alternative of RFA for the local treatment of small HCC; it is especially valuable for tumors of unfavorable location. [ABSTRACT FROM AUTHOR]
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Transarterial Ethanol Ablation for Small Hepatocellular Carcinoma (≤ 3 cm): A Comparative Study Versus Radiofrequency Ablation.
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Autor/in / Beteiligte Person: | Yu, Simon Chun Ho ; Hui, Joyce Wai Yi ; Chong, Charing Ching Ning ; Chu, Cheuk Man ; Cheung, Sunny ; Wong, John ; Lee, Kit Fai |
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Zeitschrift: | CardioVascular & Interventional Radiology, Jg. 43 (2020-05-01), Heft 5, S. 732-739 |
Veröffentlichung: | 2020 |
Medientyp: | academicJournal |
ISSN: | 0174-1551 (print) |
DOI: | 10.1007/s00270-020-02426-4 |
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