Phylogenetic and ion-response analyses reveal a relationship between gene expansion and functional divergence in the Ca2+/cation antiporter family in Angiosperms.
In: Plant Molecular Biology, Jg. 105 (2021-02-01), Heft 3, S. 303-320
Online
academicJournal
Zugriff:
Key message: Plant CaCA superfamily genes with higher tendency to retain after WGD are more gene expression and function differentiated in ion-response. Plants and animals face different environmental stresses but share conserved Ca 2+ signaling pathways, such as Ca 2+ /Cation transport. The Ca 2+ /cation antiporters superfamily (CaCAs) is an ancient and widespread family of ion-coupled cation transporters found in all kingdoms of life. We analyzed the molecular evolution progress of the family through comparative genomics and phylogenetics of CaCAs genes from plants and animals, grouping these genes into several families and clades, and identified multiple gene duplication retention events, particularly in the CAX (H + /cation exchanger), CCX (cation/Ca 2+ exchanger), and NCL (Na + /Ca 2+ exchanger-like) families. The tendency of duplication retention differs between families and gene clades. The gene duplication events were probably the result of whole-genome duplication (WGD) in plants and might have led to functional divergence. Tissue and ion-response expression analyses revealed that CaCAs genes with more highly differentiated expression patterns are more likely to be retained as duplicates than those with more conserved expression profiles. Phenotype of Arabidopsis thaliana mutants showed that loss of genes with a greater tendency to be retained after duplication resulted in more severe growth deficiency. CaCAs genes in salt-tolerant species tended to inherit the expression characteristics of their most recent common ancestral genes, with conservative ion-response expression. This study indicates a possible evolutionary scheme for cation transport and illustrates distinct fates and a mechanism for the evolution of gene duplicates. The increased copy numbers of genes and divergences in expression might have contributed to the divergent functions of CaCAs protein, allowing plants to cope with environmental stresses and adapt to a larger number of ecological niches. [ABSTRACT FROM AUTHOR]
Copyright of Plant Molecular Biology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Phylogenetic and ion-response analyses reveal a relationship between gene expansion and functional divergence in the Ca2+/cation antiporter family in Angiosperms.
|
---|---|
Autor/in / Beteiligte Person: | Zheng, Ye ; Wang, Lin-Bo ; Sun, Shu-Feng ; Liu, Shi-Ying ; Liu, Ming-Jia ; Lin, Juan |
Link: | |
Zeitschrift: | Plant Molecular Biology, Jg. 105 (2021-02-01), Heft 3, S. 303-320 |
Veröffentlichung: | 2021 |
Medientyp: | academicJournal |
ISSN: | 0167-4412 (print) |
DOI: | 10.1007/s11103-020-01088-7 |
Sonstiges: |
|