Case report: Creutzfeldt-Jakob disease presenting with anxiety symptoms in a COVID-19 post-infection patient.
In: Frontiers in Neurology, 2023-08-21, S. 1-6
Online
academicJournal
Zugriff:
Creutzfeldt-Jakob Disease (CJD) is a rare, rapidly progressive, and fatal neurodegenerative disorder. We describe a man whose initial manifestations of CJD occurred shortly after contracting Coronavirus disease 2019 (COVID-19). He first developed anxiety and short-term memory loss a few weeks after a mild COVID-19 infection. He subsequently developed parkinsonism, eventually progressed to akinetic mutism, and passed away 5 months after symptom onset. This case highlights a potential temporal relationship between COVID-19 infection and the onset of neurodegenerative symptoms. Microglia and astrocytes in the central nervous system (CNS) and 'S1' spike proteins on SARS-CoV-2 are potential mediators in neuroinflammation and neurodegeneration. [ABSTRACT FROM AUTHOR]
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Case report: Creutzfeldt-Jakob disease presenting with anxiety symptoms in a COVID-19 post-infection patient.
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Autor/in / Beteiligte Person: | Yong, Christl S. K. ; Jian-Hui Maniam, Ethan ; Chang, Cheryl W. L. ; Yexian Lai, Jonathan ; Su Hui Ho, Cyrus |
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Zeitschrift: | Frontiers in Neurology, 2023-08-21, S. 1-6 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1664-2295 (print) |
DOI: | 10.3389/fneur.2023.1239576 |
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